Tag: placebo
Placebo Plus Usual Treatment Achieves Clinically Significant Back Pain Relief
A placebo of a pill added to treatment as usual for chronic low back pain resulted in clinically significant improvements in patients who were informed about the placebo beforehand, according to a new study from Portugal. All... read more
Vitamin D and outcomes in adult critically ill patients
In critically ill patients, vitamin D administration might be associated with a reduction in mortality without significant adverse events. A large multicenter randomized trial should conclusively confirm these findings. Seven... read more
Efficacy of Oral Risperidone, Haloperidol, or Placebo for Symptoms of Delirium Among Patients in Palliative Care
In patients receiving palliative care, individualized management of delirium precipitants and supportive strategies result in lower scores and shorter duration of target distressing delirium symptoms than when risperidone... read more
No difference between placebo, amitriptyline and topiramate in reducing pediatric migraine
In this study, no significant intergroup differences between amitriptyline, topiramate and placebo for reduction in total number of headache days was observed. Amitriptyline and topiramate were associated with significantly... read more
Neuroprotective Effects of the Glucagon-Like Peptide-1 Analog Exenatide After Out-of-Hospital Cardiac Arrest
Acute administration of exenatide to comatose patients in the ICU after OHCA is feasible and safe. Exenatide did not reduce neuron-specific enolase levels and did not significantly improve a composite end point of death and... read more
Short-term Effects of High-Dose Caffeine on Cardiac Arrhythmias in Patients With Heart Failure
This randomized clinical trial evaluates the short-term effects of high-dose caffeine consumption vs placebo in patients with heart failure at increased risk for arrhythmic events. After 500 mg of caffeine administered over... read more
Examining Pantoprazole or Placebo for Stress Ulcer Prophylaxis
Pantoprazole is frequently administered to critically ill patients for prophylaxis against gastrointestinal bleeding. However, comparison to placebo has been inadequately evaluated, and pantoprazole has the potential to cause... read more
Signs of Cardioprotection Seen in Acute STEMI Patients Receiving IV Beta-blocker Post-PCI
Patients with STEMI who receive IV infusion of the beta-blocker esmolol within 60 minutes after successful PCI tend to release smaller amounts of cardiac biomarkers than those given placebo, researchers of a single-center,... read more
