Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals

Empiric treatment for suspected community-onset sepsis accounts for about half of broad-spectrum antibiotic use in US hospitals even though resistant organisms are isolated in only 7% of patients with community-onset sepsis... read more

Secretomic Approach Value in COVID-19 Viral Pneumonia Among Patients With Respiratory Distress

this article presents an innovative and promising secretomic analysis to distinguish VPP patients from NV-ICU patients using combinations of protein markers. Among the identified proteins, ficolin-3 and proteoglycan-4 appear... read more

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

Predictive Value of Multiple Scoring Systems in the Prognosis of Septic Patients with Different Infection Sites

The heterogeneity nature of sepsis is significantly impacted by the site of infection. This study aims to explore the predictive value of multiple scoring systems in assessing the prognosis of septic patients across different... read more

Secretomic Approach Value for Distinguishing Patients with COVID-19 Viral Pneumonia Among ICU Patients with Respiratory Distress

In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand... read more

Risk Factors of Post-intubation Hypotension in Severe Pneumonia Patients

Post-intubation hypotension (PIH) was one of the serious complications after Endotracheal intubation (ETI) in Severe pneumonia (SP) patients. The risk factors of PIH were investigated in SP patients to provide a theoretical... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more

Improving Outcomes in Nosocomial Pneumonia

Improving Outcomes in Nosocomial Pneumonia

Nosocomial pneumonia (NP) represents a leading nosocomial infection and results in substantial morbidity and cost. Over the last several years, the evidence has evolved which directs our approach to NP. Specifically, the... read more

Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease

Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease

Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more

A nomogram predicting pneumonia after cardiac surgery

A nomogram predicting pneumonia after cardiac surgery

Three preoperative indicators (age, preoperative malnutrition, diabetes mellitus), one intraoperative indicator (CPB > 135 min) and three postoperative indicators (moderate to severe ARDS, use of ECMO or IABP or CRRT, MV>... read more

Chest Computed Tomography Severity Score at ICU Admission and Respiratory Outcomes

Chest Computed Tomography Severity Score at ICU Admission and Respiratory Outcomes

COVID-19 patients with >50% lung involvement on Chest-CT admission presented higher chances to stay longer on invasive mechanical ventilation and more chances to developed ventilator-associated pneumonia. 121 patients... read more

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices... read more

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Omadacycline Treatment of Severe Pneumonia Complicated with ARDS During COVID-19

Metagenomic next-generation sequencing (mNGS) has a significant value in the diagnosis of Chlamydia psittaci infection. Timely treatment of omadacycline can improve prognosis and provide a promising new option for the treatment... read more

Extracorporeal Life Support for Adults

Extracorporeal Life Support for Adults

This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more

Effect of Mechanical Ventilation Under Intubation on Respiratory Tract Change of Bacterial Count

Effect of Mechanical Ventilation Under Intubation on Respiratory Tract Change of Bacterial Count

Mechanical ventilation under intubation may cause dysregulation of lower respiratory microbiota in rats. The most common 'second strike' in mechanically ventilated patients is a pulmonary infection caused by the ease with... read more

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

HFNC vs. CPAP in COVID-19 Patients with ARDS in ICU

Acute hypoxic respiratory failure in coronavirus disease 2019 (COVID-19) pneumonia has been treated with oxygen delivered by oxygen masks and non-invasive ventilation (NIV) with continuous positive airway pressure (CPAP),... read more

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

A Promising Biomarker for Early Detection of Acute Coronary Syndrome (ACS)

As found in our study, among the biomarkers used, the diagnostic accuracy of IMA was the highest and better than that of cardiac troponin I and CK-MB. Although ECG is the preferred diagnostic tool for diagnosing ACS (STEMI,... read more