Tag: research
Sepsis Reduces Bone Strength Before Morphologic Changes Are Identifiable
In a rodent sepsis model, trabecular bone strength is functionally reduced within 24 hours and is associated with a reduction in collagen and mineral elastic modulus. This is likely to be the result of altered biomechanical... read more
Clinical Care Review Systems in Healthcare
Clinical care review is the process of retrospectively examining potential errors or gaps in medical care, aiming for future practice improvement. The objective of our systematic review is to identify the current state of... read more
Early Mobility in Critically Ill Patients
Kyle Enfield, MD, speaks with Wes Ely, MD, MPH, about his talk presented at the Multiprofessional Critical Care Review: Adult course in Rosemont, Illinois entitled, "Early Mobility in Critically Ill Patients: More to Come."... read more
Cognitive Development One Year After Infantile Critical Pertussis
Infants who survive critical pertussis often have neurodevelopmental deficits. These infants may benefit from routine neurodevelopmental screening. Of 196 eligible patients, 111 (57%) completed the Mullen Scales of Early... read more
Recovery After Critical Illness: Putting the Puzzle Together
In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new... read more
Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment
Assessing alveolar recruitment at different positive end-expiratory pressure (PEEP) levels is a major clinical and research interest because protective ventilation implies opening the lung without inducing overdistention.... read more
The Utility of ICU Readmission as a Quality Indicator and the Effect of Selection
Intensive care readmission rates are used to signal quality, yet it is unclear whether they represent poor quality in the transition of care from the ICU to the ward, patient factors, or differences in survival of the initial... read more
Mastering Intensive Care – Making an Excellent Start to an Intensive Care Career
What are the biggest challenges when beginning as a fully-fledged intensive care clinician? How do you best use your senior colleagues when your experience bank is still small? What can you do to help achieve gender equity... read more
Moral distress and its contribution to the development of burnout syndrome among critical care providers
Correlation between moral distress and burnout was assessed among all intensive care unit (ICU) and the step–down unit (SDU) providers (physicians, nurses, nurse technicians and respiratory therapists). Researchers reported... read more
Antipsychotics for Prevention and Treatment of Delirium
Delirium is a common, complex and costly condition in older adults. Every year, over 7 million hospitalized Americans suffer from delirium. A recent systematic review found that 31% of critical care patients have delirium,... read more
Lower ARDS Mortality at High-Volume Intensive Care Units
For patients with acute respiratory distress syndrome (ARDS), mortality is lower in high-volume intensive care units (ICUs), according to a study presented at the annual meeting of the American Thoracic Society. The researchers... read more
Association Between Fluid Balance and Outcomes in Critically Ill Children
Fluid overload is common and is associated with substantial morbidity and mortality in critically ill children. Additional research should now ideally focus on interventions aimed to mitigate the potential for harm associated... read more
AI Can Predict Sepsis to Save Lives
Emory University researchers have created a "Sepsis Expert" algorithm that works in real time to predict the onset of sepsis, the deadly condition that often takes hold in healthcare settings. Banking on information from... read more
All Things Flu
Dr. Christopher Carroll and Dr. Jayshil Patel discussing all things flu on Reddit. They provide the facts, share the latest in research and help provide more information on how to best tackle this flu season. We are in the... read more
Enabling Machine Learning in Critical Care
Critical care units are home to some of the most sophisticated patient technology within hospitals. In parallel, the field of machine learning is advancing rapidly and increasingly touching our lives. To facilitate the adoption... read more
What have been the major recent advances in delirium research and care?
Editor-In-Chief-Elect Giuseppe Citerio discusses the recent article focused on the intensive care delirium research agenda in Intensive Care Medicine (ICM). For this evidence-based paper, a multinational and inter-professional... read more
Barriers and Facilitators to Early Rehabilitation in Mechanically Ventilated Patients
Using a theoretically driven approach, this study identified important barriers and facilitators to early rehabilitation in ICU patients. In particular, the domains of social influences and behavioral regulation were not... read more
How Patient Stories Can Improve Intensive Care
Opportunities to share stories about care, in settings away from the hospital, serve to bridge the gap between the experiences of patients and those of doctors and nurses. The 21st century re-orientation of health care towards... read more
Glycaemic Control Targets After TBI
This meta-analysis of intensive glycaemic control shows no association with reduced mortality in TBI. Intensive glucose control showed a borderline significant reduction in the risk of poor neurological outcome, but markedly... read more
Principles And Practice of Mechanical Ventilation
A comprehensive, authoritative coverage of all the clinical, pharmacological, and technical issues surrounding the use of mechanical ventilation. More than 100 authors, all of whom are at the forefront of research in their... read more
A Cool Way to Save Trauma Patients
Laboratory research like Dr. Alam's has helped to provide answers to some of these questions and demonstrated the feasibility of rapidly inducing hypothermia for exsanguinating trauma. Assuming that the pilot trial and... read more
Model Identifies Seizure Risk in Critically Ill
For critically ill patients, a model comprising six variables can identify the probability of seizure, according to a study published online Oct. 9 in JAMA Neurology. Aaron F. Struck, M.D., from the University of Wisconsin... read more
