Crystalloids vs. Colloids for Fluid Resuscitation in the ICU

Crystalloids vs. Colloids for Fluid Resuscitation in the ICU

This systematic review and meta-analysis, which included only high-level evidence from randomized, controlled trials (RCTs) conducted in intensive care settings, revealed that crystalloids were less effective than colloids... read more

Optimum Chest Compression Point for CPR in Children Revisited Using a 3D Coordinate System Imposed on CT

Optimum Chest Compression Point for CPR in Children Revisited Using a 3D Coordinate System Imposed on CT

The optimum chest compression site (P_optimum) in children is debated: European Resuscitation Council recommends one finger breadth above the xiphisternal joint, whereas American Heart Association proposes the lower sternal... read more

The Patients Were Saved. That’s Why the Families Are Suing

The Patients Were Saved. That’s Why the Families Are Suing

What happened to Beatrice Weisman before dawn on Aug. 29, 2013, was not supposed to happen: The medical staff at Maryland General Hospital found her in cardiac arrest, resuscitated her and kept her alive. The matriarch of... read more

Is a Golden Age of Resuscitation on the Horizon?

Is a Golden Age of Resuscitation on the Horizon?

Is emergency medicine on the verge of "the dawn of a new golden age of resuscitation?" That's the bold prediction from CPR innovator Keith Lurie, MD, a professor of internal and emergency medicine at the University of Minnesota,... read more

Effect of Bag-Mask Ventilation vs Endotracheal Intubation During CPR on Neurological Outcome After OHCA

Effect of Bag-Mask Ventilation vs Endotracheal Intubation During CPR on Neurological Outcome After OHCA

Among patients with out-of-hospital cardiorespiratory arrest (OHCA), the use of BMV compared with ETI failed to demonstrate noninferiority or inferiority for survival with favorable 28-day neurological function, an inconclusive... read more

Chasing Mortality Endpoints is a Fool’s Errand

Chasing Mortality Endpoints is a Fool’s Errand

"There is no mortality benefit for that." How many times have you heard that? The implication is usually the same: that intervention is a waste of time. A smart, evidence-based clinician wouldn't bother with it. But, what... read more

Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients

Fluid overload, de-resuscitation, and outcomes in critically ill or injured patients

Sepsis is associated with generalised endothelial injury and capillary leak and has traditionally been treated with large volume fluid resuscitation. Some patients with sepsis will accumulate bodily fluids. The aim of this... read more

Navigating Medical Emergencies – An interactive guide to patient management

Navigating Medical Emergencies – An interactive guide to patient management

This free eBook presents emergent clinical situations and the core tasks required of healthcare professionals needing to recognize, navigate and safely manage them. It's really about how to perform the ABCs while protecting... read more

How Do Resuscitation Teams at Top-Performing Hospitals for In-Hospital Cardiac Arrest Succeed?

How Do Resuscitation Teams at Top-Performing Hospitals for In-Hospital Cardiac Arrest Succeed?

Resuscitation teams at hospitals with high IHCA survival differ from non–top-performing hospitals. Our findings suggest core elements of successful resuscitation teams that are associated with better outcomes and form the... read more

pH-guided Fluid Resuscitation and BICAR-ICU

pH-guided Fluid Resuscitation and BICAR-ICU

The use of bicarbonate is a source of eternal disagreement. Bicarbonate has a shameful history of being abused in situations where it's unhelpful (e.g. cardiac arrest). This has impugned its reputation, giving it an aura... read more

Silent Space

Silent Space

Exhausted at the end of a busy week on service in the intensive care unit (ICU), the fellow and I are on our way to the conference room to debrief the week. The overhead code alarm disrupts the temporary lull in activity... read more

Withdrawing vs. Not Offering Cardiopulmonary Resuscitation: Is There a Difference?

In light of the SCC's Cuthbertson v. Rasouli decision, the distinction between withdrawing and not offering a medical treatment is increasingly relevant. Because CPR is a "default" treatment for cardiac arrest, it requires... read more

Preventing Harmful Delays with POCUS During Cardiac Arrest

Preventing Harmful Delays with POCUS During Cardiac Arrest

With the integration of bedside echocardiography into cardiac arrest, we now have a real-time tool to help us glean some of this critical missing information, as well as offer procedural guidance and prognostic data. However,... read more

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Haemoglobin concentration and volume of intravenous fluids in septic shock in the ARISE trial

Haemoglobin concentration decreases during resuscitation from septic shock, and has a significant but weak association with the volume of intravenous fluids administered. Median (IQR) haemoglobin concentration at baseline... read more

No Requirement for Targeted Theophylline Levels for Diuretic Effect of Aminophylline in Critically Ill Children

No Requirement for Targeted Theophylline Levels for Diuretic Effect of Aminophylline in Critically Ill Children

Aminophylline administration provided a measure of increased diuresis, regardless of dosage, and theophylline trough levels. Therefore, achieving a prescribed therapeutic trough level may not be necessary for full diuretic... read more

Moving Albumin Into the Small Volume Resuscitation Era

Moving Albumin Into the Small Volume Resuscitation Era

Physicians have an intense 70-year history of enthusiasm, skepticism, fear, and reconciliation with albumin products since their market introduction in the late 1940s. Despite its cumbersome production method and costs, albumin... read more

Functional Status Change Among Children With ECMO to Support Cardiopulmonary Resuscitation in a Pediatric Cardiac ICU

Functional Status Change Among Children With ECMO to Support Cardiopulmonary Resuscitation in a Pediatric Cardiac ICU

This is the first extracorporeal cardiopulmonary resuscitation report to examine changes in Functional Status Scale from admission (baseline) to discharge as a measure of overall functional outcome. Half of surviving patients... read more