Quantifying the Mortality Impact of Do-Not-Resuscitate Orders in the ICU

Do-not-resuscitate status is an independent risk factor for ICU mortality. This may reflect severity of illness not captured by other clinical factors, but the perceptions of the treating team related to do-not-resuscitate... read more

Quantifying the Mortality Impact of Do-Not-Resuscitate Orders in the ICU

Predicting and measuring fluid responsiveness with echocardiography

Echocardiography is an essential tool to predict and measure fluid responsiveness, according to a recent article, which provides a practical guide. Ashley Miller and Justin Mandeville outline the physiological basis of fluid... read more

Predicting and measuring fluid responsiveness with echocardiography

Updated Guidelines for Sepsis Management

In 2017 the Society for Critical Care Medicine updated its guidelines for sepsis management. These new guidelines differ significantly from ones in the past in that they no longer recommend protocolized resuscitation and... read more

Updated Guidelines for Sepsis Management

Excessive Resource Utilization

Overuse is inconsistent with professionalism because of the associated patient and societal harms and should receive equal attention as adverse events in health systems. Timely communication by inpatient specialists with... read more

Excessive Resource Utilization

A Primer on the Perils of Intravenous Fluids – Part 2

Critically-ill patients all likely have endothelial dysfunction to some degree. resuscitationThis perturbation in microvascular physiology may be underpinned by abnormal glycocalyx structure and function. Sepsis, trauma,... read more

A Primer on the Perils of Intravenous Fluids – Part 2

Central Line Versus Peripheral IV Flow Rates In Resuscitation

The indications for central venous catheters (CVCs) include invasive hemodynamic monitoring, transvenous cardiac pacing, hemodialysis, lack of peripheral venous access, administration of vasopressors, nutritional support,... read more

Central Line Versus Peripheral IV Flow Rates In Resuscitation

Normal Saline as Resuscitation Fluid in Critically Ill

The study of Van Regenmortel et al. indirectly underscores growing equipoise in the expert medical community regarding the presumed harmful effects of NS compared with balanced crystalloids. Future studies, such as the ongoing... read more

Normal Saline as Resuscitation Fluid in Critically Ill

Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation

In recent years there have been many developments in post-resuscitation care. We have investigated trends in patient characteristics and outcome following admission to UK critical care units following cardiopulmonary resuscitation... read more

Increasing survival after admission to UK critical care units following cardiopulmonary resuscitation