Predicting the Requirement for RRT in Intensive Care Patients with Sepsis

Predicting the Requirement for RRT in Intensive Care Patients with Sepsis

Sepsis is one of the most frequent causes of acute kidney injury (AKI) in critically ill patients, with initial organ impairment often followed by dysfunction in other systems. Renal dysfunction may therefore represent one... read more

Hemodynamic Consequences of Severe Lactic Acidosis in Shock States

Hemodynamic Consequences of Severe Lactic Acidosis in Shock States

Deleterious hemodynamic effects of severe lactic acidosis are largely suggested by experimental data, although not fully confirmed by human studies. Pending the effectiveness of an etiological treatment, there is no efficient... read more

Medications and RRT: We Know How to Dose, Right?

Dr. Fraser, MD, speaks with Bruce A. Mueller, PharmD, FCCP, FASN, about his talk presented at the 47th Critical Care Congress in San Antonio, Texas, entitled "Artificial Kidney Meets Mechanical Lung: Comanaging the Patient... read more

Timing of Renal Support and Outcome of Septic Shock and ARDS

Timing of Renal Support and Outcome of Septic Shock and ARDS

Early RRT initiation strategy was not associated with any improvement of 60-day mortality in patients with severe acute kidney injury and septic shock or Acute Respiratory Distress Syndrome (ARDS). Unnecessary and potentially... read more

What’s New in Severe Pulmonary Embolism?

What’s New in Severe Pulmonary Embolism?

Severe pulmonary embolism (PE) remains a major cause of mortality. For intensivists managing the most "severe" forms of PE, we highlight the main recent advances in the care of such patients including risk stratiļ¬cation,... read more

Predictors of In-Hospital Mortality After RRT Calls

Predictors of In-Hospital Mortality After RRT Calls

Despite wide adoption of rapid response teams across the United States, predictors of in-hospital mortality for patients receiving rapid response team calls are poorly characterized. Identification of patients at high risk... read more

Hyponatremia and Death in Healthy Children From Plain Dextrose and Hypotonic Saline Solutions after Surgery

Hyponatremia and Death in Healthy Children From Plain Dextrose and Hypotonic Saline Solutions after Surgery

Standards of practice should be established for postoperative IV solutions that are used to hydrate patients, particularly children. The standards should acknowledge that the administration of solutions with saline in maintenance... read more

Biomarkers for Prediction of RRT in AKI

Biomarkers for Prediction of RRT in AKI

Acute kidney injury (AKI) frequently occurs in critically ill patients and often precipitates use of renal replacement therapy (RRT). However, the ideal circumstances for whether and when to start RRT remain unclear. We performed... read more

RRT in the Critically Ill Child

RRT in the Critically Ill Child

Although renal replacement therapy (RRT) is widely used in critically ill children, there have been few comprehensive population-based studies of its use. This article describes renal replacement therapy use, and associated... read more

Impact of Nighttime RRT Activation on Outcomes of Hospitalized Patients with Acute Deterioration

Impact of Nighttime RRT Activation on Outcomes of Hospitalized Patients with Acute Deterioration

Acutely deteriorating ward patients assessed by an RRT at nighttime had a higher risk of in-hospital mortality. This work identifies important shortcomings in health service provision and quality of care outside daytime hours,... read more

Outcomes in Patients with Vasodilatory Shock and RRT Treated with Intravenous Angiotensin II

Outcomes in Patients with Vasodilatory Shock and RRT Treated with Intravenous Angiotensin II

Acute kidney injury (AKI) requiring renal replacement therapy in severe vasodilatory shock is associated with an unfavorable prognosis. Angiotensin II treatment may help these patients by potentially restoring renal function... read more

Too Much SALT on the ICU?

Too Much SALT on the ICU?

There has a been a little flutter of activity in the #FOAMed world this week about two trials published in the NEJM on the subject of balanced fluids in the care of critically ill patients, and also on admitted patients in... read more

Acute Kidney Injury in Sepsis

Acute Kidney Injury in Sepsis

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU and accounts for approximately half of all such... read more

Renal Recovery – RRT Modality

Renal Recovery – RRT Modality

Renal recovery - does the choice of renal replacement therapy matter?... read more