Optimizing Continuous RRT in the ICU

Optimizing Continuous RRT in the ICU

The consideration of acute kidney injury, its incidence and its impact on the outcome of patients has grown continuously in recent years, leading to an increase in the use of renal replacement therapy (RRT) techniques. Recent... read more

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery

In patients with sepsis, recovery by hospital discharge is associated with long-term survival similar to patients without AKI. Of the 1742 patients who survived to hospital discharge, stage 2–3 AKI occurred in 262 (15%),... read more

A Pilot Study Evaluating the Effect of Cooler Dialysate Temperature on Hemodynamic Stability During Prolonged Intermittent RRT in AKI

A Pilot Study Evaluating the Effect of Cooler Dialysate Temperature on Hemodynamic Stability During Prolonged Intermittent RRT in AKI

Acute kidney injury (AKI) requiring renal replacement therapy (RRT) is associated with high morbidity and mortality. Complications of renal replacement therapy include hemodynamic instability with ensuing shortened treatments,... read more

CRRT for Sepsis-induced Acute Kidney Injury

CRRT for Sepsis-induced Acute Kidney Injury

Sepsis-induced acute kidney injury (SI-AKI) represents the first cause of AKI in ICUs, and renal replacement therapy (RRT) is frequently applied in advanced AKI stages. The debate between 'rescue' indications for RRT start... read more

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

A modified Delphi process to identify, rank and prioritize quality indicators for CRRT care in critically ill patients

We developed a prioritized list of 13 QIs for continuous renal replacement therapy (CRRT) care. Future work should focus on developing validated benchmarks for these QIs and implementing them into CRRT programs. We conducted... read more

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Choice of Catheter Size for Infants in Continuous Renal Replacement Therapy

Small size central vascular catheters display optimal rheologic performances in terms of pressures and flows particularly when the renal replacement therapy (RRT) device is equipped with pumps proportional to central vascular... read more

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Complications of Regional Citrate Anticoagulation: Accumulation or Overload?

Based on recent recommendations, the use of Regional Citrate Anticoagulation (RCA) is likely to increase dramatically throughout the world. RCA protocols should aim to minimize the amount of net citrate load delivered to... read more

Caring for Critically Ill Patients in Humanitarian Settings

Caring for Critically Ill Patients in Humanitarian Settings

Critical care medicine is far from the first medical field to come to mind when humanitarian action is mentioned, yet both critical care and humanitarian action share a fundamental purpose to save the lives and ease the suffering... read more

RRT Board Exam: Dominate the Hemodynamic and ECG Portion of the Respiratory Therapy Board Exam

RRT Board Exam: Dominate the Hemodynamic and ECG Portion of the Respiratory Therapy Board Exam

Our RRT Board exam series helps you study smarter, not harder. Instead of giving you information overload, we focus solely on the most recent NBRC TMC and clinical simulation exam matrix. Start feeling more confident and... read more

Dosing Adjuvant Vitamin C in Critically Ill Patients Undergoing CRRT

Dosing Adjuvant Vitamin C in Critically Ill Patients Undergoing CRRT

We read with great interest the recent letter to Critical Care by Marik and Hooper. Vitamin C is increasingly recognized as a crucial compound to alleviate morbidity in critically ill patients. Vitamin C concentrations, however,... read more

Tigecycline in Critically Ill Patients on Continuous RRT

Tigecycline in Critically Ill Patients on Continuous RRT

Despite high dialysability, dialysis clearance displayed only a minor contribution to tigecycline elimination, being in the range of renal elimination in patients without AKI. No dose adjustment of tigecycline seems necessary... read more

RRT Board Exam: Mechanical Ventilation

RRT Board Exam: Mechanical Ventilation

There’s nothing better than feeling confident and relaxed on exam day! Knowing that years of late night study sessions and unpaid clinical rotations are coming to an end just feels….well, absolutely fantastic! Of course,... read more

Effect of Early vs Delayed Initiation of RRT on Mortality in Critically Ill Patients With AKI

Effect of Early vs Delayed Initiation of RRT on Mortality in Critically Ill Patients With AKI

Among critically ill patients with Acute Kidney Injury (AKI), early Renal Replacement Therapy (RRT) compared with delayed initiation of RRT reduced mortality over the first 90 days. Further multicenter trials of this intervention... read more

Early Versus Late Initiation of Renal Replacement Therapy in Critically Ill Patients

Early Versus Late Initiation of Renal Replacement Therapy in Critically Ill Patients

Early initiation of renal replacement therapy (RRT) effect on survival and renal recovery of critically ill patients is still uncertain. We aimed to systematically review current evidence comparing outcomes of early versus... read more