Effect of Omega 3 polyunsaturated fatty acids in major burn patients

Effect of Omega 3 polyunsaturated fatty acids in major burn patients

The inclusion of ω-3 PUFAs in a low fat diet in ICU burned patients was associated with significant clinical benefits compared to a conventional low fat diet, with lower rates of severe sepsis, septic shock and pyloric dysfunction.... read more

Impact of transfusion on patients with sepsis admitted in ICU

Impact of transfusion on patients with sepsis admitted in ICU

Red blood cell transfusion (RBCT) threshold in patients with sepsis remains a matter of controversy. A threshold of 7 g/dL for stabilized patients with sepsis is commonly proposed, although debated. The aim of the study was... read more

Towards precision medicine for sepsis patients

Towards precision medicine for sepsis patients

Over the last decade it has become clear that the immunological response and clinical course in sepsis patients is too complex to simply regard it as hyperinflammation-induced organ failure. In contrast to the previous belief... read more

Recognize Sepsis as Separate Cause of Illness and Death

Recognize Sepsis as Separate Cause of Illness and Death

Sepsis should be recognized as a separate cause of illness and death around the world. This focus would help efforts to prevent sepsis by improving hygiene, nutrition and vaccination rates and also lead to timely treatment,... read more

Sepsis Algorithm a Deadly Marker

Sepsis Algorithm a Deadly Marker

An attempt by a Phoenix, AZ, hospital to develop a marker for deadly sepsis instead found that the algorithm identified patients at an increased risk of dying. Increasingly, algorithms govern daily life, playing an important... read more

Disruption of the microbiota across multiple body sites in critically ill children

Disruption of the microbiota across multiple body sites in critically ill children

Microbiota in critically ill children differs sharply from the microbiota of healthy children and adults. Acknowledgement of dysbiosis associated with critical illness could provide opportunities to modulate the microbiota... read more

New Blood Draw Protocol can reduce risks for pediatric patients

New Blood Draw Protocol can reduce risks for pediatric patients

Researchers report that implementing a checklist-style set of procedures appears to cut almost in half the number of potentially unnecessary blood culture draws in critically ill children without endangering doctors'... read more

Outsourced Hospital Cleaning linked to MRSA

Outsourced Hospital Cleaning linked to MRSA

Analysis of English NHS hospitals suggests that employing private as opposed to in-house cleaners is a false economy. While it may reduce costs, it could also raise risk of infection by methicillin-resistant Staphylococcus... read more

Think Sepsis and Act Fast

Think Sepsis and Act Fast

New attention to sepsis including revised definitions, updated guidelines, and new CMS reporting requirements aims to save lives through prevention and prompt and effective management of infections. CDC released a new Vital... read more

Blood culture decision algorithm tied to PICU admissions

Blood culture decision algorithm tied to PICU admissions

A standardized approach to blood cultures in the pediatric ICU successfully reduced collections from central venous catheters, investigators at a single center reported, with no subsequent uptick in adverse events.... read more

Three-year mortality in 30 day survivors of critical care with AKI

Three-year mortality in 30 day survivors of critical care with AKI

Acute kidney injury was not an independent risk factor for 3-year mortality among 30-day survivors. Increased 3-year mortality among patients with AKI who survive critical illness may not be related to AKI per se, but rather... read more

Wires and Peripherally Inserted Central Catheters

An increasing number of patients are being admitted to critical care units with multiple chronic medical conditions. In some of these patients, intravenous access is a challenge. With a concern for indwelling catheter infections,... read more

Sepsis on the Wards Manuscript Available Open Access

Sepsis on the Wards Manuscript Available Open Access

Surviving Sepsis Campaign supporter, the Gordon and Betty Moore Foundation, recently funded open access with its Sepsis on the Wards grant for original research.... read more

Plasma cytokine levels predict response to corticosteroids in septic shock

Plasma cytokine levels predict response to corticosteroids in septic shock

Plasma concentration of selected cytokines is a potential predictive biomarker to identify septic shock patients that may benefit from treatment with corticosteroids.... read more

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

The medical records of 957 patients were retrieved from a prospectively collected database. Serum lactate improved accuracy for values higher than 4 mmol/L in the no-dysfunction and septic shock groups.... read more

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

Impact of a high loading dose of amikacin in patients with severe sepsis or septic shock

With a loading dose of 30 mg/kg of amikacin, concentration was potentially suboptimal. The pharmacodynamic target (60 mg/L < C max < 80 mg/L) recommended by French guidelines was reached in 41.8% of patients and was... read more