Long COVID Associated with Reduced Circulating Serotonin Levels

Long COVID Associated with Reduced Circulating Serotonin Levels

Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been formulated... read more

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Enteral melatonin initiated within 48 h of ICU admission did not reduce the prevalence of delirium compared to placebo. These findings do not support the routine early use of melatonin in the critically ill. A total of... read more

Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors in pregnancy

Selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors in pregnancy

This position statement provides guidance for the monitoring, care, and follow-up of newborns exposed to selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) in utero. Depression... read more

Serotonin Syndrome

Serotonin Syndrome

Serotonin syndromes comes up a lot in critical care medicine. Sometimes we are admitting patients because of a primary diagnosis of serotonin syndrome. Other times we are afraid of causing serotonin syndrome ourselves, due... read more