Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

Over the 10‑year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU... read more

On Diagnosing Sepsis

On Diagnosing Sepsis

Two years ago, a panel appointed by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine, referred to as a consensus conference, proposed a new definition for sepsis and new diagnostic... read more

Managing Sepsis and Septic Shock Current Guidelines and Definitions

Managing Sepsis and Septic Shock Current Guidelines and Definitions

While sepsis defies simple definition, it's generally understood to be a clinical syndrome caused by infection that may have profound adverse physiologic consequences. Although its precise incidence is unknown, sepsis is... read more

Defining Sepsis on the Wards: Comparing Two Sepsis Definitions

Defining Sepsis on the Wards: Comparing Two Sepsis Definitions

Sepsis is defined as a dysregulated host response to infection, resulting in acute organ dysfunction. Although the condition has been thoroughly studied in the intensive care unit (ICU), accurate data collection outside of... read more

New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality

New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality

qSOFA and CRB outperformed SIRS and presented better clinical usefulness as prompt tools for patients with community-acquired pneumonia in the emergency department. Among the tools for a comprehensive patient assessment,... read more

Early Oseltamivir Therapy Improves the Outcome in Critically Ill with Influenza

Early Oseltamivir Therapy Improves the Outcome in Critically Ill with Influenza

This real-life study emphasizes oseltamivir efficacy on in-hospital outcome when administrated within 2 days of the onset of symptoms. Even if physicians' awareness of the influenza disease has been undeniably enhanced... read more

SOFA Effective Pediatric Version

SOFA Effective Pediatric Version

An age-adjusted version of the Sequential Organ Failure Assessment score for sepsis has been found to be at least as good, if not better than, other pediatric organ dysfunction scores at predicting in-hospital mortality.... read more

What’s new in the extracorporeal treatment of sepsis?

Clinical research has shown that endotoxin is indeed circulating in the blood of up to 50% of sepsis shock patients and associated with impaired clinical outcome. In view of the pivotal role of endotoxin in sepsis patients,... read more

SOFA score may be best to identify sepsis in the ICU

SOFA score may be best to identify sepsis in the ICU

Among critically ill patients admitted to the ICU with a suspected infection, defining sepsis by an increase of two or more points in the Sequential Organ Failure Assessment (SOFA) score yielded greater prognostic accuracy... read more