Airway Management of The Morbidly Obese Patient

Obesity is a major health care dilemma. All aspects of medical care, including anesthesia, are affected by it. All physiologic systems are altered by obesity, which imparts a higher risk for complications in the perioperative... read more

5-Year Trends of Critical Care Practice and Outcomes

According to researchers in the U.S., analyses of patients, practices, and outcomes from a large geographically dispersed sample of adult ICUs revealed trends of increasing age and acuity, higher rates of adherence to best... read more

Moral Distress in PICU and Neonatal ICU Practitioners

In this single-center, cross-sectional study, we found that moral distress is present in PICU and neonatal ICU health practitioners and is correlated with burnout, uncertainty, and feeling unsupported. The main outcome was... read more

Early Troponin I in Critical Illness and its Association with Hospital Mortality

TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more

Benzodiazepines and Delirium in ICU Patients

We have learned an extraordinary amount about ICU delirium over the last 2 decades, which is associated with increased duration of mechanical ventilation, length of hospital stay, long-term cognitive impairment, and mortality... read more

An Alternative Consent Process for Minimal Risk Research in the ICU

Seeking consent for minimal risk research in the ICU poses challenges, especially when the research is time-sensitive. Our aim was to determine the extent to which ICU patients or surrogates support a deferred consent process... read more

The Lactate Dilemma

After a long and exhausting discussion with an inferior human being, a cardiologist, which happens to be an old friend, I decided to write some thoughts about lactate. So, I'll do like I do in my lectures, which is state... read more

NIH Herpesvirus Study Leads to Discovery of Potential Broad-Spectrum Antiviral

Scientists studying how regulated herpes simplex virus (HSV) infection unexpectedly found that inhibiting EZH2/1 suppressed viral infection. The research group, from the National Institute of Allergy and Infectious Diseases... read more

Impact of PICU Admission on Family Financial Status

A child's pediatric intensive care unit (PICU) admission may have wide-ranging family implications. We assessed nonmedical out-of-pocket expenses (NMOOPEs) and disruptions in work and normal life for parents with a child... read more

A Methodological Study to Develop a Standard Protocol for Central Line Catheter Care of ICU Patients

This study aims to develop a standard operational protocol (SOP) for central line catheter care for nurses. Central line based infection is the most significant complication in critical care setting. It is a challenge for... read more

Delays in Antibiotic Administration for Sepsis

Todd Fraser, MD, speaks with Christopher W. Seymour, MD, MSc, about the article, "Delays From First Medical Contact to Antibiotic Administration for Sepsis," published in Critical Care Medicine. Dr. Seymour's article contends... read more

Whole Body Hyperthermia Appeared to Reduce Depression Symptoms

Whole-body hyperthermia holds promise as a safe, rapid-acting, antidepressant modality with a prolonged therapeutic benefit. Results from the current study suggest that WBH holds promise as a safe, rapid-acting, antidepressant... read more

Increased ICU Costs for Opioid Overdoses

ICU costs for treating opioid overdose patients increased 58% in a seven-year span, and annual deaths almost doubled, according to a study that included 162 academic hospitals. ICU admissions increased 34% over the study... read more

Extended ICU Visitation Model Reduces Delirium

In this medical-surgical ICU, an extended visitation model was associated with reduced occurrence of delirium and shorter length of delirium/coma and ICU stay. Two hundred eighty-six patients were enrolled (141 restricted... read more

nutritionDay ICU

An worldwide prevalence study to determine the nutrition practice in the ICUs and the associated outcome across the world, a yearly 1 day cross sectional audit was performed from 2007 to 2013. This very large collaborative... read more

Potentially modifiable factors contributing to sepsis-associated encephalopathy

Acute renal failure and common metabolic disturbances represent potentially modifiable factors contributing to sepsis-associated encephalopathy. However, a true causal relationship has yet to be demonstrated. Our study confirms... read more

Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis

Secondary retrospective analysis of a single-center sepsis registry. Vasoactive-Inotropic Score in pediatric sepsis patients is independently associated with important clinically relevant outcomes including ICU length of... read more

Safety Hazards During Intrahospital Transport

A prospective observational study. Data from participant observations of the intrahospital transport process were collected over a period of 3 months. Findings suggest that intrahospital transport is a hazardous process for... read more

Most ICU Patients Underfed

A large international multicentre cohort study shows that most of the patients are underfed during their ICU stay. In their findings published in the journal Clinical Nutrition, researchers say most of the patients in intensive... read more

SOFA Effective Pediatric Version

An age-adjusted version of the Sequential Organ Failure Assessment score for sepsis has been found to be at least as good, if not better than, other pediatric organ dysfunction scores at predicting in-hospital mortality.... read more

Stress Ulcer Prophylaxis in the ICU (SUP-ICU)

Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported. The aim of the SUP-ICU trial is to asses the overall... read more

Double Mortality Risk for Depressed Heart Disease Patients

Among 24,000 patients with heart disease studied over many years, those who suffered from depression were at twice the risk of dying, according recently published findings from Intermountain Healthcare. A statistical analysis... read more