Tag: study
Can Electronic Alerts Help Identify Sepsis in Sick Children?
A two-step electronic alert system successfully reduced missed sepsis diagnoses in children by 76 percent. The new pediatric protocol, which incorporates the use of vital signs, risk factors, and a clinician's judgment,... read more
This Startup Could Revolutionize How We Fight Infectious Diseases
Karius Test has raised $50 million to develop a novel technology that can detect more than 1,000 infectious diseases, without requiring the usual trial-and-error tests. The test is expensive at $2,000, and is meant for use... read more
Muscle Oxygenation as Indicator of Shock Severity
The aim of this pilot study was to evaluate the potential of a new noninvasive optical measurement of muscle oxygenation (MOx) to identify shock severity in patients with suspected sepsis. We demonstrate that noninvasive... read more
International Survey of Critically Ill Children with Acute Neurological Insults
Margaret Parker, MD, MCCM, speaks with Ericka L. Fink, MD, MS, about the PANGEA study (Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment), published in the April 2017 issue... read more
Improving Long-Term Outcomes Research for ARF
Alison Turnbull, DVM, MPH, PhD discusses the heterogeneity in outcome measures in our field and the need for a Core Outcome Measurement Set (COMS) to standardize reporting of important outcomes. As part of the consensus process,... read more
Readmissions for Recurrent Sepsis: New or Relapsed Infection?
Sepsis hospitalizations are frequently followed by hospital readmissions, often for recurrent sepsis. However, it is unclear how often sepsis readmissions are for relapsed/recrudescent vs. new infections. The aim of this... read more
Anabolic and Anticatabolic Agents in Critical Care
Profound metabolic derangements occur in critically ill patients; this hypermetabolic response is a major contributor to adverse outcomes. Despite the pharmacological therapies currently available to counteract this devastating... read more
Examining Mechanical Chest Compressions
Mechanical chest compression (CC) during cardiopulmonary resuscitation (CPR) with AutoPulse or LUCAS devices has not improved survival from cardiac arrest. Cohort studies suggest risk of excess damage. Therefore, Koster et... read more
Clinical Impact of COPD on Non-cystic Fibrosis Bronchiectasis
Clinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry. Patients with BE related to COPD have the same... read more
Doctors frustrated that electronic records steal time from patients
Researchers asked doctors licensed to practice in Rhode Island the question: How does using an EHR affect your interaction with patients? They got an earful. Most who responded complained that electronic records undermined... read more
Patients with postoperative delirium more likely to suffer dementia
Delirium is common in elderly hospitalized patients, affecting an estimated 14 - 56% of patients. It frequently manifests as a sudden change in behavior, with patients suffering acute confusion, inattention, disorganized... read more
Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease
Obstructive sleep apnea (OSA) is associated with impaired renal function, but uncertainty exists over whether OSA treatment can influence renal outcomes. Objectives: To determine the effects of continuous positive airway... read more
Link Between Diabetes and Hospital Readmission Rates
Patients with diabetes have higher rates of hospital readmission compared with patients without diabetes, according to a pilot study published in Clinical Diabetes and Endocrinology. In the first study, the readmission rate... read more
Efficient Organization of ICUs with a Focus on Quality: The Non-Physician Provider
Adequate staffing in ICUs is an increasing problem worldwide. We would like to elaborate on staffing problems that arise in ICUs across Europe, including the Dutch situation. This staffing problem is caused by the increased... read more
Role of Preventability in Redefining Failure to Rescue Among Major Trauma Patients
Failure to rescue (FTR) is defined as death after a major complication and has been adopted as a measure of quality in surgical patients. Current definitions of FTR are limited because they do not account for the influence... read more
Reducing Brain Injury After Cardiac Arrest
Therapeutic hypothermia (TH) (32-34°C for 24 hours) should be mandatory practice for patients who are comatose after being resuscitated from out-of-hospital cardiac arrest, if the initial cardiac rhythm is either pulseless... read more
How to Beat Burnout
Burnout takes a toll on physicians, their patients, and their practices. Short visits, complicated patients, lack of control, electronic health record stress, and poor work-home balance can lead to physicians leaving practices... read more
Targeted Temperature Management and Neurologic Outcome After Out-of-Hospital Cardiac Arrest
In this randomized clinical trial enrolling 355 adults with out-of-hospital cardiac arrest, there was no significant difference in favorable neurologic outcome at 6 months for those treated for 48 hours (69%) vs 24 hours... read more
Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock
Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more
Enhancing the Usability of Systematic Reviews by Improving the Consideration and Description of Interventions
The importance of adequate intervention descriptions in minimizing research waste and improving research usability and reproducibility has gained attention in the past few years. Nearly all focus to date has been on intervention... read more
Web-based ICU Communication Improves Patient Experience and Outcomes
Researchers at Brigham and Women's Hospital (BWH) have developed a web-based program that uses team communication and engagement to improve patient experience and outcomes. The study enrolled 1,075 ICU patients and provided... read more
Why are doctors plagued by depression and suicide?
Suicide among medical students and doctors has been a largely unacknowledged phenomenon for decades, obscured by secrecy and shame. Now, it’s beginning to emerge from the shadows. More than 62,000 people, many of them medical... read more
