Tag: study

Delirium: Thinking Clearly About a Foggy Issue

Benzodiazepines are one of the leading causes of delirium. These drugs are already falling out of favor in critical care settings for other reasons; they are not easily titratable, and research suggests they can prolong a... read more

Assessing Postoperative Pulmonary Complications After Noncardiothoracic Surgery

In this multicenter study in 1202 American Society of Anesthesiologists physical status 3 patients undergoing noncardiothoracic surgery requiring 2 hours or more of general anesthesia with mechanical ventilation, at least... read more

Rude Surgeons Likely to Make Mistakes

A new study finds surgeons with a history of patient complaints about their personalities or attitude are more likely to make mistakes in the operating room. Researchers compared surgical outcomes with patient reports of... read more

Wide variations found in evaluation of newborns for sepsis

The evaluation of well-appearing term infants for early-onset sepsis (EOS) varies considerably among hospitals, with some doing extensive work-ups and giving antibiotics while others simply observe and provide newborn routine... read more

MR-proADM Accuracy Superior for Sepsis Mortality Prediction

The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin... read more

Carotid Stenting Technology Has More Appeal

Ten-year follow-up from the CREST trial and 5-year follow-up from the ACT I study, presented at least year's International Stroke Conference, showed that carotid artery stenting (CAS) holds up well over the long term... read more

Sepsis Readmissions Compared With Other Medical Conditions

This study uses data from a US readmissions database to assess whether sepsis hospitalizations account for a higher proportion of unplanned 30-day readmissions than hospitalizations for acute myocardial infarction, heart... read more

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more

Interventions to improve antibiotic prescribing practices for hospital inpatients

This review includes 221 studies (58 RCTs, and 163 NRS). Most studies were from North America (96) or Europe (87). The remaining studies were from Asia (19), South America (8), Australia (8), and the East Asia (3). We found... read more

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Three distinct models for reporting risk-adjusted mortality rates among hospitals and physicians performing PCI in New York State demonstrate a high degree of agreement, despite variation in how they handle the inclusion... read more

Crizanlizumab use lowers rates of sickle cell crises

Patients with sickle cell disease treated with high-dose crizanlizumab experienced lower annualized rates of sickle cell crisis compared to placebo treatment, regardless of their baseline use of hydroxyurea. Those treated... read more

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

The results of our trials showed that prophylaxis with low-molecular-weight heparin for the 8 days after knee arthroscopy or during the full period of immobilization due to casting was not effective for the prevention of... read more

Social Media Helps Forecast Outbreak Transmission Patterns

A new study suggests then when epidemiological data are scarce, social media and Internet reports can be reliable tools for forecasting infectious disease outbreaks. Researchers at Georgia State University and the U.S. National... read more

Manufacturer guidelines fall short for endoscope reprocessing

A just-published study finds that current endoscopic manufacturer cleaning instructions for a wide range of GI, urological and respiratory devices used in diagnostic procedures still fail to protect patients from the risk... read more

Hydrocortisone Fails to Prevent Septic Shock

Hydrocortisone failed to reduce the risk of septic shock in severe sepsis patients in recent research, though its authors held out hope that a larger study could show a better result. Current guidelines recommend hydrocortisone... read more

Benefits and harms of duloxetine for treatment of stress urinary incontinence

Duloxetine was significantly better than placebo in terms of percentage change in weekly incontinence episodes (mean difference - 13.56%, 95% confidence interval [CI] -21.59% to -5.53%) and change in Incontinence Quality... read more

Transcatheter Aortic Valve Replacement in Younger Individuals

When a patient has an aortic valve that requires replacement because the native valve is diseased, 2 types of valves can be used - mechanical valves or bioprosthetic valves, also known as tissue valves. Bioprosthetic valves... read more

Transmission of Staphylococcus aureus between health-care workers, the environment, and patients in ICU

Between Oct 31, 2011, and Dec 23, 2012, we sampled 198 health-care workers, 40 environmental locations, and 1854 patients; 1819 isolates were sequenced. Median nasal carriage rate of S aureus in health-care workers at 4-weekly... read more

Clinical Massage, Guided Imagery Show Promise as Tools to Relieve Pain, Anxiety and Insomnia for Hospitalized Patients

Clinical massage and guided imagery may have a substantial, positive impact on patients' comfort at a very low cost, according to a study published in Critical Care Nurse. Researchers with Beaumont Health System in Royal... read more

A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients

This phase II study has shown that IC43 vaccination of ventilated ICU patients produced a significant immunogenic effect. P. aeruginosa infection rates did not differ significantly between groups. In the absence of any difference... read more

Medical residents spend more time using computers than on patient interaction

At a teaching hospital in Switzerland, internal medicine residents spent an average of 52.4% and 47.9% of the day shift and evening shift, respectively, on activities indirectly related to the patient and spent 28.0% and... read more

The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families

Over the past 20 years, critical care has matured in a myriad of ways resulting in dramatically higher survival rates for our sickest patients. For millions of new survivors comes de novo suffering and disability called "the... read more