Ten-year follow-up from the CREST trial and 5-year follow-up from the ACT I study, presented at least year's International Stroke Conference, showed that carotid artery stenting (CAS) holds up well over the long term against carotid endarterectomy (CEA) in asymptomatic and symptomatic patients with severe carotid stenosis. CREST-2 is looking into how revascularization fares over medical therapy alone in asymptomatic patients, but it features an unusual, two-arm design that may preclude direct comparisons between stenting and surgery.

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