Tag: study
Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock
Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more
Enhancing the Usability of Systematic Reviews by Improving the Consideration and Description of Interventions
The importance of adequate intervention descriptions in minimizing research waste and improving research usability and reproducibility has gained attention in the past few years. Nearly all focus to date has been on intervention... read more
Web-based ICU Communication Improves Patient Experience and Outcomes
Researchers at Brigham and Women's Hospital (BWH) have developed a web-based program that uses team communication and engagement to improve patient experience and outcomes. The study enrolled 1,075 ICU patients and provided... read more
Why are doctors plagued by depression and suicide?
Suicide among medical students and doctors has been a largely unacknowledged phenomenon for decades, obscured by secrecy and shame. Now, it’s beginning to emerge from the shadows. More than 62,000 people, many of them medical... read more
Reduced Risk of Acute Exacerbation of COPD after Bariatric Surgery
Obesity is common among individuals with chronic obstructive pulmonary disease (COPD) and associated with increased COPD morbidities. However, little is known about the impact of weight reduction on COPD-related outcomes... read more
Preoperative Cognitive Performance and Delirium Associated With Future Dementia in Older People After Cardiac Surgery
Delirium after cardiac surgery commonly, occurs in 25–67 percent of patients. Delirium is a neuropsychiatric syndrome characterized by a change in cognition fluctuates, develops over a short period of time and has an underlying... read more
In Treating Sepsis, Questions About Timing and Mandates
The question of whether Rory's Regulations save lives isn’t asked or answered in the recent study. Sepsis deaths were already decreasing in the United States before the mandate, and determining its contribution to... read more
Effectiveness and Safety of Magnesium Replacement in Critically Ill Patients Admitted to the ICU
Rules of thumb for the replacement of electrolytes, including magnesium, in critical care settings are used, despite minimal empirical validation of their ability to achieve a target serum concentration. This study's... read more
Palliative Care in Advanced HF Makes a Big Difference in Rare Controlled Trial
Patients with end-stage heart failure who received palliative care from an interdisciplinary team, along with usual evidence-based care, significantly improved in functional, psychosocial, and spiritual well-being compared... read more
Heart Rate Variability in Critical Care Medicine
Heart rate variability (HRV) has been used to assess cardiac autonomic activity in critically ill patients, driven by translational and biomarker research agendas. Several clinical and technical factors can interfere with... read more
Clinical Experience With IV Angiotensin II Administration
Angiotensin II is an endogenous hormone with vasopressor and endocrine activities. This is a systematic review of the safety of IV angiotensin II. Adverse events associated with angiotensin II were infrequent; however, exacerbation... read more
Should All Massively Transfused Patients Be Treated Equally?
Although balanced resuscitation has become integrated into massive transfusion practice, there is a paucity of evidence supporting the delivery of high ratios of plasma and platelet to RBCs in the nontrauma setting. This... read more
Optimal Timing of RRT in Patients with AKI in the Context of Sepsis
Among 620 patients enrolled in AKIKI, 494 (80%) had sepsis and 413 (67%) septic shock. This can help to suggest recommendations in septic patients with AKI. AKIKI showed no significant difference in mortality between early... read more
Impact of Telemedicine Monitoring of Community ICUs on Interhospital Transfers
In a regional healthcare system, implementation of a tele-ICU program is associated with an increase in interhospital transfers from less resourced ICUs to the referral center, a trend that is not readily explained by increased... read more
PICU Repeated and Unplanned Readmissions Within 1 Year
Unplanned readmissions occurred in a sizable minority of PICU patients. Patients with complex chronic conditions and particular conditions were at much higher risk for readmission. In this multi-institutional study, we found... read more
Detecting impaired myocardial relaxation in sepsis with a novel tissue Doppler parameter
Left ventricular diastolic dysfunction is associated with mortality outcomes in severe sepsis and septic shock. There are ongoing issues with diagnosing diastolic dysfunction in this cohort, partly owing to the poor applicability... read more
Frequency of Exacerbations in Patients with COPD
Present treatment strategies to stratify exacerbation risk in patients with chronic obstructive pulmonary disease (COPD) rely on a history of two or more events in the previous year. We aimed to understand year to year variability... read more
