Tag: study
Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill
Among critically ill patients with acute kidney injury, exposure to positive fluid balance, compared with negative fluid balance, has been associated with mortality and impaired renal recovery. However, it is unclear whether... read more
Antimicrobial Stewardship and Appropriate Antimicrobial Prescribing in Hospitals
This study examines whether an antimicrobial stewardship approach grounded in behavioral theory and focusing on preserving prescriber autonomy and participation is associated with appropriateness of antimicrobial prescribing... read more
New Ways for Research Findings to Reach More People
When it comes to sharing new research findings with the world, Twitter has emerged as a key tool for scientists - and for the journals where they publish their findings. But a new study shows a way for that research to reach... read more
Implications of Prevalent Noncardiac Disease in the Cardiac ICU
Half of >1000 patients of admitted to the cardiac intensive care unit (ICU) at a major tertiary-care center over about 1 year also had acute respiratory failure, acute kidney injury, or sepsis. Those with lung or kidney... read more
New Study: Economic Cost to Surviving ARDS
Research published today in the American Journal of Respiratory and Critical Care Medicine sheds light on the economic toll on survivors of acute respiratory distress syndrome. Nearly 50% of survivors who worked before they... read more
FDA Approves Label Changes for Pediatric General Anesthetic and Sedation Drugs
The FDA has approved labeling changes regarding the use of general anesthetic and sedation medicines in children younger than 3 years. General anesthetic and sedation drugs are necessary for patients, including young children... read more
Extra Corporeal Carbon Dioxide Removal
In patients with chronic obstructive airway disease and hypercapneic acidosis, who are failing non-invasive ventilation, does extra corporeal carbon dioxide removal compared to non-invasive ventilation alone, reduce the... read more
Clinical Sensors lands $1.5 million in NIH grants for sepsis work
Clinical Sensors, a startup based in Research Triangle Park, North Carolina, has been awarded two Small Business Research Grants from the National Institutes of Health. Together, the grants total $1.5 million and are earmarked... read more
Single IRBs in Multisite Trials
On June 21, 2016, the US government announced changes that are arguably the most significant of the last quarter century concerning the protection of human research participants - a requirement for use of central or single... read more
Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia
Metabolomics is a tool that has been used for the diagnosis and prognosis of specific diseases. The purpose of this study was to examine if metabolomics could be used as a potential diagnostic and prognostic tool for H1N1... read more
Manual vs. Integrated Automatic Load-distributing Band CPR with Equal Survival after out of Hospital Cardiac Arrest
Between March 5, 2009 and January 11, 2011 a randomized, unblinded, controlled group sequential trial of adult out-of-hospital cardiac arrests of presumed cardiac origin was conducted at three US and two European sites. After... read more
Big Data Detects Sepsis In Major Hospitals
Data analytics have found that large medical facilities have higher rates of death from sepsis than their smaller hospital counterparts. Researchers from Houston Methodist Hospital recently used Big Data analytics to learn... read more
Hemodialysis and Survival in Intubated Salicylate-Poisoned Patients
Salicylate-poisoned patients can be incredibly complex and severely ill. Secondary to the significant acid-base abnormalities that can accompany salicylate poisoning, hemodialysis (HD) is sometimes required to facilitate... read more
No Major Azithromycin Arrhythmia Risk in Huge European Cohort
Current use of azithromycin (Zithromax/Zmax, Pfizer) was linked with a twofold increased risk of ventricular arrhythmia compared with no antibiotic use, but this risk disappeared when azithromycin use was compared with amoxicillin... read more
Admission to the ICU is Associated With Changes in the Oral Mycobiome
A prospective exploratory study was conducted to characterize the oral mycobiome at baseline and determine whether changes occur after admission to the intensive care unit (ICU). We found that ICU admission is associated... read more
Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department
In this multicenter prospective cohort study involving 879 patients with suspected infection treated at the emergency department, the qSOFA was better at predicting in-hospital mortality with an area under the receiver operating... read more
The effect of day of the week on short- and long-term mortality for emergency general surgery
The effect of day of the week on outcome after surgery is the subject of debate. The aim was to determine whether day of the week of emergency general surgery alters short- and long-term mortality. Dr Mike Gillies and... read more
Effect of an automated notification system for deteriorating ward patients on clinical outcomes
We performed a prospective before-and-after study in all patients admitted to two clinical ward areas in a district general hospital in the UK. We examined the effect on clinical outcomes of deploying an electronic automated... read more
