Tag: study
More NOAC Comparisons See More Bleeding With Rivaroxaban: Is the ‘Writing on the Wall’?
Evidence is mounting, albeit from observational studies, that while all of the non-vitamin K antagonist oral anticoagulants (NOACs) appear to have similar efficacy in terms of stroke reduction in atrial fibrillation, they... read more
Levosimendan Doesn’t Prevent Acute Organ Dysfunction
For adults with sepsis, levosimendan does not prevent acute organ dysfunction.... read more
Empirical micafungin treatment doesn't improve survival
Empirical treatment with micafungin seems not to increase invasive fungal infection (IFI)-free survival at 28 days for patients with intensive care unit (ICU)-acquired sepsis with Candida colonization.... read more
Low Diastolic Blood Pressure Linked to Subclinical Myocardial Damage and Coronary Events: ARIC Analysis
Very low diastolic blood pressure (DBP) is associated with an increased risk of subclinical myocardial damage, particularly among individuals with diastolic pressures less than 60 mm Hg, according to the results of a new... read more
Adjunctive azithromycin reduces risk of non-elective cesarean post-operative infection: The C/SOAP trial
Women receiving azithromycin in addition to standard antibiotic prophylaxis for cesarean section (c-section) were 49% less likely to develop endometritis and postoperative wound infections compared to those who received only... read more
Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge
Over a recent 10-year period, there has been an improvement in the prescription of evidence-based medical therapy for patients who survive and are discharged from hospital after an MI, a new analysis shows.... read more
Researchers identify genes that may cause gum disease
Columbia University scientists say they have identified 41 master regulator genes that may cause gum disease in a first-of-its-kind study.... read more
Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients
All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of... read more
New Ecosystem Test Strongly Predicts Ovarian Cancer Survival
Assessing the cell ecosystems at sites where ovarian cancer has spread round the body strongly predicts the chances of surviving from the disease, a new study reports. ... read more
Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation
There was a total of 52 240 new starts of dabigatran and 66 651 new starts of rivaroxaban during the study period. Rivaroxaban was associated with a non-significant decrease in thromboembolic stroke. There was also a non-significant... read more
Gene could lead to ALS therapies
Researchers from Ben-Gurion University of the Negev say their new gene study could lead to new treatments for amyotrophic lateral sclerosis, or ALS.... read more
Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials
Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control.... read more
Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical Patients
Current evidence suggests that symbiosis of commensal microflora play a significant role in health and illness. The effect that commensal microflora play in critical care is less well known.... read more
Smoking, vitamin D deficiency linked to early MS disability
Severe vitamin D deficiency and current smoking predicted accumulated disability in patients with clinically isolated syndrome, which can be a precursor to the development of multiple sclerosis.... read more
ICDs appear not to improve overall survival in non-ischemic systolic HF
This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more
HDAC inhibitors show promise against cancer stem cells
A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate... read more
VTE history in female relatives increases absolute thrombotic risk
A family history of thrombosis in women may increase the risk for venous thromboembolism in women taking oral contraceptives, according to the results of a cohort study.... read more
Omega-3 could help prevent environmentally induced lupus
A new study suggests that docosahexaenoic acid - a type of omega-3 present in fish oil and dietary supplements - has the potential to prevent lupus, after finding the fatty acid blocked a known trigger of the disease.... read more
