Value of Expedited Drug Approvals for Cancer Care

Value of Expedited Drug Approvals for Cancer Care

This study examines potential benefits of cancer drugs approved by the FDA on the basis of surrogate endpoints.... read more

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more

Lower threshold for abdominal aortic aneurysm repair linked to reduced mortality

Lower threshold for abdominal aortic aneurysm repair linked to reduced mortality

The study examined the differences between the threshold of repair and aneurysm-related mortality in England and the United States. The rate of hospitalization due to a ruptured aneurysm and aneurysm-related death was significantly... read more

Stroke: New drug limits brain damage and promotes repair

Stroke: New drug limits brain damage and promotes repair

Research using rats shows a drug already approved for other conditions reduces the number of brain cells killed by stroke and promotes birth of new ones.... read more

Researchers developing biomaterial with potential to treat vascular bleeding

Researchers developing biomaterial with potential to treat vascular bleeding

Researchers at Mayo Clinic, Harvard Medical School and the Massachusetts Institute of Technology are developing a biomaterial that has potential to protect patients at high risk for bleeding in surgery.... read more

Risk of hemorrhage with statins and stroke prevention drug combination

Risk of hemorrhage with statins and stroke prevention drug combination

Two commonly used statins can increase the risk of hemorrhage when combined with dabigatran etexilate, a drug often used for preventing stroke in patients with atrial fibrillation.... read more

Negative pressure irrigation and endoscopic necrosectomy through man-made sinus tract in infected necrotizing pancreatitis

Negative pressure irrigation and endoscopic necrosectomy through man-made sinus tract in infected necrotizing pancreatitis

This four-step approach is effective in treating IPN and adds no extra risk to patients when compared with other latest step-up strategies. The two novel techniques (NPI and ED) could offer distinct clinical benefits without... read more

Children in ICU recover faster without nutrition

Children in ICU recover faster without nutrition

Researchers in Belgium found the standard practice of feeding children as soon as they get to ICU to help them recover faster is wrong.... read more

HSCI researchers use color tagging system to track development of blood stem cells

HSCI researchers use color tagging system to track development of blood stem cells

Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to track the development of the blood system and trace the lineage of adult blood cells travelling through the vast networks of... read more

Mount Sinai Researchers Use Computer Algorithms to Diagnose HCM

Mount Sinai Researchers Use Computer Algorithms to Diagnose HCM

Computer algorithms can automatically interpret echocardiographic images and distinguish between pathological hypertrophic cardiomyopathy (HCM) and physiological changes in athletes' hearts.... read more

Lean six methodology can cut health care-linked infections

Lean six methodology can cut health care-linked infections

Application of the Lean Six Sigma (LSS) methodology can reduce the risk of health care-associated infections (HAI) among patients undergoing surgical procedures.... read more

Beta-blocker Therapy Seems to Boost Post-PCI Outcomes in Patients With ACS

Beta-blocker Therapy Seems to Boost Post-PCI Outcomes in Patients With ACS

Guidelines from the American College of Cardiology and American Heart Association recommend using beta-blockers in patients with STEMI and NSTEMI, although studies looking at the effects of treatment have provided somewhat... read more

Study Examines Rates, Causes of ED Visits for Adverse Drug Events

Study Examines Rates, Causes of ED Visits for Adverse Drug Events

The prevalence of emergency department (ED) visits for adverse drug events (ADEs) in the United States was estimated to be four per 1,000 individuals in 2013 and 2014, and the most common drug classes involved were anticoagulants,... read more

New technique keeps donor lungs viable longer

New technique keeps donor lungs viable longer

A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds.... read more

Pneumonia Rates Linked to Hospital Ventilators Have Not Dropped, Says Study

Pneumonia Rates Linked to Hospital Ventilators Have Not Dropped, Says Study

Contrary to data published by the CDC, a study led by a UConn Health researcher concluded that ventilator-associated pneumonia is still a significant risk to patients.... read more

Combined Data Show Superiority of LAMA/LABA in COPD

Combined Data Show Superiority of LAMA/LABA in COPD

Patients with chronic obstructive pulmonary disease (COPD) experienced significantly fewer acute exacerbations when a long-acting muscarinic antagonist (LAMA) was added to a long-acting beta agonist (LABA) than when an inhaled... read more

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more