New Ecosystem Test Strongly Predicts Ovarian Cancer Survival

New Ecosystem Test Strongly Predicts Ovarian Cancer Survival

Assessing the cell ecosystems at sites where ovarian cancer has spread round the body strongly predicts the chances of surviving from the disease, a new study reports. ... read more

Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation

Rivaroxaban associated with increased bleeding risk compared with dabigatran in nonvalvular atrial fibrillation

There was a total of 52 240 new starts of dabigatran and 66 651 new starts of rivaroxaban during the study period. Rivaroxaban was associated with a non-significant decrease in thromboembolic stroke. There was also a non-significant... read more

Gene could lead to ALS therapies

Gene could lead to ALS therapies

Researchers from Ben-Gurion University of the Negev say their new gene study could lead to new treatments for amyotrophic lateral sclerosis, or ALS.... read more

Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials

Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials

Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control.... read more

Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical Patients

Dysbiosis Across Multiple Body Sites in Critically Ill Adult Surgical Patients

Current evidence suggests that symbiosis of commensal microflora play a significant role in health and illness. The effect that commensal microflora play in critical care is less well known.... read more

Smoking, vitamin D deficiency linked to early MS disability

Smoking, vitamin D deficiency linked to early MS disability

Severe vitamin D deficiency and current smoking predicted accumulated disability in patients with clinically isolated syndrome, which can be a precursor to the development of multiple sclerosis.... read more

ICDs appear not to improve overall survival in non-ischemic systolic HF

ICDs appear not to improve overall survival in non-ischemic systolic HF

This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more

HDAC inhibitors show promise against cancer stem cells

HDAC inhibitors show promise against cancer stem cells

A group of researchers, led by scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has shown that histone deacetylase (HDAC) inhibitors have the potential to eliminate... read more

VTE history in female relatives increases absolute thrombotic risk

VTE history in female relatives increases absolute thrombotic risk

A family history of thrombosis in women may increase the risk for venous thromboembolism in women taking oral contraceptives, according to the results of a cohort study.... read more

Omega-3 could help prevent environmentally induced lupus

Omega-3 could help prevent environmentally induced lupus

A new study suggests that docosahexaenoic acid - a type of omega-3 present in fish oil and dietary supplements - has the potential to prevent lupus, after finding the fatty acid blocked a known trigger of the disease.... read more

HPV Vaccine More Effective Than Thought

HPV Vaccine More Effective Than Thought

The vaccine against human papillomavirus (HPV) infection, which doctors believe causes most cases of cervical cancer, appears even more effective than believed, a new study finds.... read more

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Scientists reveal how signals from pathogenic bacteria reach danger sensors of cells

Researchers at St. Jude Children's Research Hospital have discovered the way signals from infectious bacteria gain entry into the cytoplasm of host cells to activate disease-fighting inflammasomes. Inflammasomes are... read more

Dramatic remissions seen in immunotherapy trial of blood cancer patients

Dramatic remissions seen in immunotherapy trial of blood cancer patients

Many patients with advanced blood cancers who are receiving experimental, "living" immunotherapy as part of a clinical trial are experiencing sustained remissions, according to preliminary results of the ongoing... read more

Opioid-Related Overdoses And Deaths Are On The Rise In The ICU

Opioid-Related Overdoses And Deaths Are On The Rise In The ICU

The rate of opioid hospitalizations and overdose deaths has only gotten worse in the past few years, new research finds.... read more

Genetic Loci Linked to Acute Kidney Injury

Genetic Loci Linked to Acute Kidney Injury

Four single-nucleotide polymorphisms at two loci identified in discovery, replication populations.... read more

COPD epidemic could overwhelm healthcare systems within two decades

COPD epidemic could overwhelm healthcare systems within two decades

Health authorities should brace themselves for an epidemic of chronic obstructive pulmonary disease (COPD) over the next two decades, despite a decline in smoking rates, according to a new study from the University of British... read more