Tag: study
Fluid Responsiveness in a Hemodynamically Unstable Patient
Only half of patients who are hemodynamically unstable will respond to a fluid bolus. There are no historical or physical examination findings that can help us decide whether a patient is a fluid responder, but we must treat... read more
Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation-Derived Optimal Cerebral Perfusion Pressure
These mechanistic simulations provide insight into the empiric basis of optimal cerebral perfusion pressure and the significance of PRx and Δ CPP. PRx and optimal cerebral perfusion pressure deviations do not directly reflect... read more
Crystalloids vs. Colloids for Fluid Resuscitation in the ICU
This systematic review and meta-analysis, which included only high-level evidence from randomized, controlled trials (RCTs) conducted in intensive care settings, revealed that crystalloids were less effective than colloids... read more
Risk Factors for 1-Year Mortality and Hospital Utilization Patterns in Critical Care Survivors
One in five ICU survivors die within 1 year, with advanced age and comorbidity being significant predictors of outcome, leading to high resource use. Care process factors indicating high system stress were associated with... read more
Effect of a Program Combining Transitional Care and Long-term Self-management Support on Outcomes of Hospitalized Patients With COPD
In a single-site randomized clinical trial of patients hospitalized due to Chronic obstructive pulmonary disease (COPD), a 3-month program that combined transition and long-term self-management support resulted in significantly... read more
More Healthcare Workers Born Outside the USA
The healthcare sector continues to lead the way in hiring. A new study found more than 16% of healthcare professionals surveyed in 2016 were born outside the U.S.... read more
Bedside Ultrasound Assessment of Lung Reaeration in Patients With Blunt Thoracic Injury Receiving High-Flow Nasal Cannula Oxygen Therapy
High-flow nasal cannula oxygen therapy may be considered as an initial respiratory therapy for trauma patients with blunt chest injury. High-flow nasal cannula therapy could improve lung aeration as noted by the transthoracic... read more
Antimicrobial Chemical Tied to Antibiotic Resistance Genes in Dust
Most people have heard about antibiotic-resistant germs. But how about antibiotic-resistant dust? A new Northwestern University study has found that an antimicrobial chemical called triclosan is abundant in dust — and linked... read more
Most Physicians Disenchanted With Their Profession
Seven out of ten physicians would not recommend their profession to their children or other family members, and more than half are thinking about retiring within the next five years, including one-third of those under the... read more
Study Shows More Than 50% of Americans Have at Least 1 Chronic Health Condition, Mental Disorder, or Substance Use Issue
Overall, 18.4% of adults reported a mental illness in the past year, and 8.6% reported substance abuse/dependence during the same time. Nearly 40% had 1 or more chronic medical conditions in their lifetimes, and 14.7% were... read more
Epidemiology of Mechanically Ventilated Patients Treated in ICU and non-ICU Settings in Japan
A large proportion of Japanese patients on mechanical ventilation (MV) were treated in non-ICU settings. Analysis of administrative data indicated preliminary that hospital mortality rates in these patients were higher in... read more
Association of Driving Pressure With Mortality Among Ventilated Patients With ARDS
Our study confirmed an association between higher driving pressure and higher mortality in mechanically ventilated patients with acute respiratory distress syndrome (ARDS). These findings suggest a possible range of driving... read more
Nurse Staffing, Nursing Assistants and Hospital Mortality
Lower RN staffing and higher levels of admissions per RN are associated with increased risk of death during an admission to hospital. These findings highlight the possible consequences of reduced nurse staffing and do not... read more
Reprint of Recovery Programme for ICU Survivors Has No Effect on Relatives’ Quality of Life
The recovery programme intended for intensive care survivors did not have an effect on the relatives. Future recovery programmes should be targeted to help both patient and family, and future research should be conducted... read more
A Multicentre Randomised Controlled Trial of Levetiracetam vs. Phenytoin for Convulsive Status Epilepticus in Children
Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzodiazepines,... read more
Bacteria ‘alarm clock’ may cause repeat infections in patients
Scientists have discovered a bacteria 'alarm clock' that wakes dormant Salmonella in the body, allowing the bug to trigger a repeat infection. The researchers, from Imperial College London, say the 'alarm clock' is shared... read more
Seeing the Present Through the Past
As an MD-PhD candidate, now in the second year of a history of medicine PhD, I often reflect on the role of history in the medical school classroom and at the bedside. Medical history is a useful way to understand the roots... read more
The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis
The combination of PCT and CRP or presepsin alone improves the accuracy of diagnosis of neonatal sepsis. However, further studies are required to confirm these findings. A total of 28 studies enrolling 2661 patients were... read more
