Study Shows More Than 50% of Americans Have at Least 1 Chronic Health Condition, Mental Disorder, or Substance Use Issue

Study Shows More Than 50% of Americans Have at Least 1 Chronic Health Condition, Mental Disorder, or Substance Use Issue

Overall, 18.4% of adults reported a mental illness in the past year, and 8.6% reported substance abuse/dependence during the same time. Nearly 40% had 1 or more chronic medical conditions in their lifetimes, and 14.7% were... read more

Epidemiology of Mechanically Ventilated Patients Treated in ICU and non-ICU Settings in Japan

Epidemiology of Mechanically Ventilated Patients Treated in ICU and non-ICU Settings in Japan

A large proportion of Japanese patients on mechanical ventilation (MV) were treated in non-ICU settings. Analysis of administrative data indicated preliminary that hospital mortality rates in these patients were higher in... read more

Association of Driving Pressure With Mortality Among Ventilated Patients With ARDS

Association of Driving Pressure With Mortality Among Ventilated Patients With ARDS

Our study confirmed an association between higher driving pressure and higher mortality in mechanically ventilated patients with acute respiratory distress syndrome (ARDS). These findings suggest a possible range of driving... read more

Nurse Staffing, Nursing Assistants and Hospital Mortality

Nurse Staffing, Nursing Assistants and Hospital Mortality

Lower RN staffing and higher levels of admissions per RN are associated with increased risk of death during an admission to hospital. These findings highlight the possible consequences of reduced nurse staffing and do not... read more

Reprint of Recovery Programme for ICU Survivors Has No Effect on Relatives’ Quality of Life

Reprint of Recovery Programme for ICU Survivors Has No Effect on Relatives’ Quality of Life

The recovery programme intended for intensive care survivors did not have an effect on the relatives. Future recovery programmes should be targeted to help both patient and family, and future research should be conducted... read more

A Multicentre Randomised Controlled Trial of Levetiracetam vs. Phenytoin for Convulsive Status Epilepticus in Children

A Multicentre Randomised Controlled Trial of Levetiracetam vs. Phenytoin for Convulsive Status Epilepticus in Children

Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzodiazepines,... read more

Bacteria ‘alarm clock’ may cause repeat infections in patients

Bacteria ‘alarm clock’ may cause repeat infections in patients

Scientists have discovered a bacteria 'alarm clock' that wakes dormant Salmonella in the body, allowing the bug to trigger a repeat infection. The researchers, from Imperial College London, say the 'alarm clock' is shared... read more

Seeing the Present Through the Past

Seeing the Present Through the Past

As an MD-PhD candidate, now in the second year of a history of medicine PhD, I often reflect on the role of history in the medical school classroom and at the bedside. Medical history is a useful way to understand the roots... read more

The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis

The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis

The combination of PCT and CRP or presepsin alone improves the accuracy of diagnosis of neonatal sepsis. However, further studies are required to confirm these findings. A total of 28 studies enrolling 2661 patients were... read more

Feasibility and Perceptions of PICU Diaries

Feasibility and Perceptions of PICU Diaries

The use of ICU diaries in the PICU setting is feasible and perceived as beneficial by families of critically ill children. Future studies are needed to better understand if PICU diaries may objectively improve psychologic... read more

Do State Regulations on Nurse Staffing Make a Difference in ICU Outcomes?

Do State Regulations on Nurse Staffing Make a Difference in ICU Outcomes?

In the recent issue of Critical Care Medicine, Law and colleagues published an evaluation of the impact of changes in Massachusetts state regulations mandating that nurse staffing levels on critical care units be set at 1:1... read more

Sedation and Neurodevelopmental Outcomes in PICU

Sedation and Neurodevelopmental Outcomes in PICU

As little as 30 minutes of exposure to anesthetic and sedative agents may adversely affect the developing brain. Safe, humane management of critically ill infants requires the use of sedative agents, often for prolonged periods.... read more

Discontinuing 5-ASA Safe Upon Anti-TNF Induction for Ulcerative Colitis

Discontinuing 5-ASA Safe Upon Anti-TNF Induction for Ulcerative Colitis

Patients with ulcerative colitis who discontinue 5-aminosalicylate therapy once they begin anti-TNF therapy do not appear at great risk for adverse clinical events, according to research published in Gut. Researchers analyzed... read more

Mortality of civilian patients with suspected traumatic hemorrhage receiving pre-hospital transfusion of packed red blood cells compared to pre-hospital crystalloid

Mortality of civilian patients with suspected traumatic hemorrhage receiving pre-hospital transfusion of packed red blood cells compared to pre-hospital crystalloid

In a single centre UK HEMS study, in patients with suspected traumatic hemorrhage who received a PRBC transfusion there was an observed, but non-significant, reduction in mortality at 6 h and 28 days, also reflected in... read more