Tag: study
Cerebral Autoregulation in the Prediction of Delayed Cerebral Ischemia and Clinical Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage Patients
High initial pressure reactivity index, presumably reflecting early brain injury, but not oxygen reactivity index, was associated with delayed cerebral ischemia and worse clinical outcome in poor-grade subarachnoid hemorrhage... read more
Oral Versus Intravenous Antibiotics for the Treatment Of Bone and Joint Infection
Oral antibiotic therapy is non-inferior to IV therapy when used during the first six weeks in the treatment for bone and joint infection, as assessed by definitive treatment failure within one year of randomisation. These... read more
The Association Between ARDS Hospital Case Volume and Mortality
In this cohort, at both an individual- and hospital-level, higher acute respiratory distress syndrome hospital case volume is associated with lower acute respiratory distress syndrome hospital mortality. We analyzed 2,686... read more
Prevalence of Pulmonary Embolism in Patients With Syncope
The results of the present study confirm that pulmonary embolism (PE) is rarely identified in patients presenting to the ED with syncope. Although PE should be considered as a differential diagnosis in every patient, not... read more
Outcomes of Ethics Consultations in Adult ICUs
Our review identified outcome-based assessment as the predominant measure used to report effectiveness of clinical ethics consultation consultations. In particular, clinical ethics consultation decreased ICU length of stay... read more
Inspiratory Muscle Training Does Not Improve Clinical Outcomes in 3-week COPD Rehabilitation
The value of inspiratory muscle training (IMT) in pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) is unclear. The RIMTCORE (Routine Inspiratory Muscle Training within COPD Rehabilitation) randomised... read more
Training Approaches for the Deployment of a Mechanical Chest Compression Device
Pit-crew training, compared with standard training, did not improve team deployment of a mechanical chest device in a simulated cardiac arrest scenario. Twenty teams participated in this study, each comprising three clinicians.... read more
Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment
Assessing alveolar recruitment at different positive end-expiratory pressure (PEEP) levels is a major clinical and research interest because protective ventilation implies opening the lung without inducing overdistention.... read more
The Utility of ICU Readmission as a Quality Indicator and the Effect of Selection
Intensive care readmission rates are used to signal quality, yet it is unclear whether they represent poor quality in the transition of care from the ICU to the ward, patient factors, or differences in survival of the initial... read more
Prognostic Effects of Delirium Motor Subtypes in Hospitalized Older Adults
One in three acutely ill hospitalized older adults who suffered hypo-active or mixed delirium died in the hospital. Clinicians should be aware that hypo-active symptoms of delirium, whether shown exclusively or in alternation... read more
Physician Genders and the Likelihood of ICU Admission in Hospital with Restricted ICU Bed Capacity
Despite the evidence that the patient gender is an important component in the intensive care unit (ICU) admission decision, the role of physician gender and the interaction between the two remain unclear. We demonstrated... read more
The Effect of 6% Hydroxyethyl Starch (130/0.4) On AKI in Pediatric Cardiac Surgery
We have evaluated the effect of a colloid solution on acute kidney injury in paediatric cardiac surgery. A total of 195 patients were randomly divided into an hydroxyethyl starch group and a control group. In the starch group,... read more
Targeting Transfusion-Related Acute Lung Injury
We propose that the most promising therapeutic strategies to explore are interleukin-10 therapy, down-modulating C-reactive protein levels, targeting reactive oxygen species, or blocking the interleukin-8 receptors; all focused... read more
Effect of Nocturnal Sound Reduction on the Incidence of Delirium in ICU Patients
The incidence of delirium in ICU patients was significantly reduced after implementation of a nocturnal sound-reduction protocol. However, reported sleep quality did not improve. A significant difference in slope in the percentage... read more
Bedside Limited Echocardiography by the Emergency Physician Is Accurate During Evaluation of the Critically Ill Patient
Our study suggests that PEP sonographers are capable of obtaining images that permit accurate assessment of LVF and IVC volume. BLEEP can be performed with focused training and oversight by a pediatric cardiologist. We conducted... read more
Transfers From ICU to Hospital Ward
Little is known about documentation during transitions of patient care between clinical specialties. Therefore, we examined the focus, structure and purpose of physician progress notes for patients transferred from the intensive... read more
Stress Ulcer Prophylaxis in ICU Patients Receiving Enteral Nutrition
Our results suggested that in patients receiving enteral feeding, pharmacologic SUP is not beneficial and combined interventions may even increase the risk of nosocomial pneumonia. We searched PubMed, Embase, and the Cochrane... read more
The Overlooked Danger of Delirium in Hospitals
The condition, once known as "ICU psychosis," disproportionately affects seniors and those who have been heavily sedated—and the delusions can last long after they're discharged. Patients treated in intensive-care units... read more
Do We Need New Trials of Procalcitonin-Guided Antibiotic Therapy?
Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assessed the effect... read more
Lower ARDS Mortality at High-Volume Intensive Care Units
For patients with acute respiratory distress syndrome (ARDS), mortality is lower in high-volume intensive care units (ICUs), according to a study presented at the annual meeting of the American Thoracic Society. The researchers... read more
Association Between Fluid Balance and Outcomes in Critically Ill Children
Fluid overload is common and is associated with substantial morbidity and mortality in critically ill children. Additional research should now ideally focus on interventions aimed to mitigate the potential for harm associated... read more
Prompt Administration of Antibiotics and Fluids in the Treatment of Sepsis
We conclude that antibiotic therapy is highly time sensitive, and efforts should be made to deliver this critical therapy as early as possible in sepsis, perhaps extending into the first point of medical contact outside the... read more
