Tag: study
Clinical Impact of External Laryngeal Manipulation During Laryngoscopy on Tracheal Intubation Success in Critically Ill Children
External laryngeal manipulation during direct laryngoscopy was associated with lower initial tracheal intubation attempt success in critically ill children, even after adjusting for underlying differences in patient factors... read more
Sepsis Patients can be Risk Stratified at the Time of Diagnosis
Multicenter Meta-Analysis Reveals Sepsis Patients can be Risk Stratified at the Time of Diagnosis Demonstrating Potential to Improve Critical Care Medicine on a Global Scale. For this study, the team identified a large collection... read more
Tracheal Intubation During Adult In-Hospital Cardiac Arrest and Survival
This cohort study uses data from the Get With The Guidelines-Resuscitation registry to investigate the association between tracheal intubation during adult in-hospital cardiac arrest and survival to hospital discharge. In... read more
Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
Over the 10‑year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU... read more
Management of the Traumatized Airway
There is a lack of evidence-based approach regarding the best practice for airway management in patients with a traumatized airway. Airway trauma may not be readily apparent, and its evaluation requires a high level of suspicion... read more
Diagnostic Accuracy of Delirium Assessment Methods in Critical Care Patients
Delirium is a disorder of decreased ability to focus, sustain or shift attention, change in cognition and or perception. The main objective was to evaluate the diagnostic accuracy of Confusion Assessment Method for the ICU... read more
Prone Positioning of ARDS Patients
A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study. While prone positioning (PP) has been shown to improve patient survival in... read more
Trends of Incidence and Risk Factors of VAP in Elderly Patients Admitted to French ICUs
This study assesses trends and risk factors of ventilator-associated pneumonia (VAP) according to age, particularly in the elderly admitted to French ICUs between 2007 and 2014. Ventilator-associated pneumonia incidence is... read more
Clinical Care Review Systems in Healthcare
Clinical care review is the process of retrospectively examining potential errors or gaps in medical care, aiming for future practice improvement. The objective of our systematic review is to identify the current state of... read more
Tracheal Intubation in Critically Ill Patients
We performed a systematic review of randomized controlled studies evaluating any drug, technique or device aimed at improving the success rate or safety of tracheal intubation in the critically ill. We identified 22 trials... read more
Distributions and Behavior of Vital Signs in Critically Ill Children by Admission Diagnosis
This is the first study reporting distributions of continuously measured physiologic variables and trends in their behavior according to admission diagnosis in critically ill children. Differences detected between and within... read more
REPROVE: Ceftazidime-avibactam Noninferior to Meropenem for Nosocomial Pneumonia
Ceftazidime-avibactam was noninferior to meropenem for nosocomial pneumonia including ventilator-associated pneumonia (VAP) from gram-negative organisms, results from the REPROVE trial demonstrated. Nosocomial or hospital-acquired... read more
Is Overall Mortality the Right Composite Endpoint in Clinical Trials of ARDS?
Most deaths in acute respiratory distress syndrome (ARDS) patients are not directly related to lung damage but to extrapulmonary multisystem organ failure. It would be challenging to prove that specific lung-directed therapies... read more
Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients
As delirium is a common manifestation in critically ill patients and is associated with worse clinical outcomes, we sought to characterize the reversibility of delirium after discontinuation of sedation and to determine whether... read more
Conceptualizing Post Intensive Care Syndrome in Children
Post Intensive Care Syndrome in pediatrics (PICS-p) will help illuminate the phenomena of surviving childhood critical illness and guide outcomes measurement in the field. Empirical studies are now required to validate and... read more
The Sound of Air: Point-of-Care Lung Ultrasound in Perioperative Medicine
Lung ultrasound (LUS) has emerged as an effective and accurate goal-directed diagnostic tool that can be applied in real time for the bedside assessment of patients with respiratory symptoms and signs. Lung ultrasound has... read more
Cognitive Development One Year After Infantile Critical Pertussis
Infants who survive critical pertussis often have neurodevelopmental deficits. These infants may benefit from routine neurodevelopmental screening. Of 196 eligible patients, 111 (57%) completed the Mullen Scales of Early... read more
Long-Term Cognitive Impairment after Hospitalization for Community-Acquired Pneumonia
Recent studies suggest older patients hospitalized for community-acquired pneumonia are at risk for new-onset cognitive impairment. The characteristics of long-term cognitive impairment after pneumonia, however, have not... read more
