Tag: study
Effects of Physical Activity on Poststroke Cognitive Function
Despite the social, health, and economic burdens associated with cognitive impairment poststroke, there is considerable uncertainty about the types of interventions that might preserve or restore cognitive abilities. The... read more
Intensive Care Syndrome: Promoting Independence and Return to Employment (InS:PIRE)
Many patients suffer significant physical, social and psychological problems in the months and years following critical care discharge. At present, there is minimal evidence of any effective interventions to support this... read more
Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus
Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality. Currently, the impact of interspecies interaction... read more
A tailored multicomponent program to reduce discomfort in critically ill patients
Critically ill patients are exposed to stressful conditions and experience several discomforts. The primary objective was to assess whether a tailored multicomponent program is effective for reducing self‑perceived discomfort.... read more
What’s the Effective Antibiotic Dosing in Critically Ill Patients?
Mortality due to severe infections in the intensive care unit (ICU) remains high despite recent therapeutic advancements. It is believed that ICU pathogens are relatively different from those in the general wards as they... read more
Initial Nutritional Management During NIV and Outcomes
Patients starting noninvasive ventilation (NIV) to treat acute respiratory failure are often unable to eat and therefore remain in the fasting state or receive nutritional support. Nearly three-fifths of patients receiving... read more
The Prognostic Value of MRI in Moderate and Severe TBI
Traumatic brain injury (TBI) is a major cause of death and disability, yet many predictors of outcome are not precise enough to guide initial clinical decision-making. Although increasingly used in the early phase following... read more
Diagnostic Accuracy of Point-of-Care Ultrasound Performed by Pulmonary Critical Care Physicians for Right Ventricle Assessment in Patients With Acute Pulmonary Embolism
This is the first study to evaluate pulmonary critical care fellows' and intensivists' use of goal-directed echocardiography in diagnosing right ventricular dysfunction in acute pulmonary embolism. Pulmonary Critical Care... read more
Factors Associated With Pediatric Ventilator-Associated Conditions in Six U.S. Hospitals
A newly proposed surveillance definition for ventilator-associated conditions among neonatal and pediatric patients has been associated with increased morbidity and mortality among ventilated patients in cardiac ICU, neonatal... read more
Use of Wearable Devices for Post-discharge Monitoring of ICU patients
Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness. We found that wearable devices could... read more
iSepsis – A 30ml/kg Bolus: Yes or No -The Results
The results of both surveys are not surprising. This recommendation has never been prospectively tested in a large RCT and has little supporting evidence. Imagine the American Heart Association (AHA) or the American Diabetes... read more
Spotlight Interview: The World of Fluids
Looking at the data from a new perspective, the article "Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill" published in Critical Care Medicine in August 2017,... read more
Multicenter Assessment of Sedation and Delirium Practices in the ICU in Poland
A majority of Polish ICUs do not adhere to international guidelines regarding sedation and delirium practices. There continues to be inadequate use of sedation and delirium monitoring tools. High usage of benzodiazepines... read more
Lowering systolic blood pressure would save more than 100,000 lives per year, study finds
Intensive treatment to lower systolic (top number) blood pressure to below 120 would save more than 100,000 lives per year in the United States, say scientists. Two thirds of the lives saved would be men and two thirds would... read more
ICU Diary Impact on Patients and Families Wellbeing
The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs. This study will provide new insights on the impact of ICU diaries on... read more
Association of the Hospital Readmissions Reduction Program Implementation With Readmission and Mortality Outcomes in Heart Failure
Among fee-for-service Medicare beneficiaries discharged after heart failure hospitalizations, implementation of the HRRP was temporally associated with a reduction in 30-day and 1-year readmissions but an increase in 30-day... read more
The YEARS Study – Simplified Diagnostic Management of PE
The clinical diagnosis of pulmonary embolism (PE) can be challenging given its variable presentation, requiring dependence on objective testing. Decision instruments such as PERC and the Wells' score help stratify patients... read more
Definitive Global Transfusion Study Supports Patient Safety and Outcomes
Lower thresholds for blood transfusions during cardiac surgery have proven to be safe and provide good patient outcomes compared to traditional thresholds, according to the largest research study ever performed in this area.... read more
Sepsis mortality linked to concentration of critical care fellowships
Higher survival rates for sepsis were more concentrated in the Northeast and metropolitan areas in the Western regions of the United States. Compared with other parts of the United States, survival rates for sepsis were highest... read more
Enhancing Delirium Case Definitions in Electronic Health Records
Delirium is an acute confusional state, associated with morbidity and mortality in diverse medically ill populations. Delirium may be better captured by composite outcomes, including both administrative claims data and elements... read more
Is Intravenous Administration of Iodixanol Associated with Increased Risk of AKI, Dialysis, or Mortality?
Among patients at the highest perceived risk of post-contrast Acute Kidney Injury (AKI), intravenous administration of iodixanol for contrast material enhanced CT was not an independent risk factor for AKI, dialysis, or... read more
