Airway Closure during Surgical Pneumoperitoneum in Obese Patients

Airway Closure during Surgical Pneumoperitoneum in Obese Patients

In obese patients, complete airway closure is frequent during anesthesia and is worsened by Trendelenburg pneumoperitoneum, which increases airway opening pressure and alveolar pressure: besides preventing alveolar derecruitment,... read more

Transcutaneous CO2 vs. End-tidal CO2 in Neonates and Infants Undergoing Surgery

Transcutaneous CO2 vs. End-tidal CO2 in Neonates and Infants Undergoing Surgery

EtCO2 underestimates PvCO2 values in neonates and infants under general anesthesia. TcPCO2 closely approximates venous blood gas values, in both the NICU and non-NICU samples. We, therefore, conclude that tcPCO2 is a more... read more

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery

Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery

Intravenous lidocaine administered during and after cardiac surgery did not reduce postoperative cognitive decline at 6 weeks. Among the 420 allocated subjects who returned for 6-week follow-up, there was no difference in... read more

Thiamine Deficiency: Pearls and Pitfalls

Thiamine Deficiency: Pearls and Pitfalls

Although thiamine would not be isolated until 1911, the clinical syndrome of thiamine deficiency was recognized as far back as 2700 BC, when the term "beriberi", meaning "wasted wasted" was first coined in China. Nearly 5,000... read more

Reproducibility Trial Publishes Two Conclusions For One Paper

Reproducibility Trial Publishes Two Conclusions For One Paper

The British Journal of Anaesthesia's unusual experiment is designed to broaden replicability efforts beyond just methods and results. How deeply an anaesthetist should sedate an elderly person when they have surgery is... read more

Surgical Critical Care and Emergency Surgery: Clinical Questions and Answers

Surgical Critical Care and Emergency Surgery: Clinical Questions and Answers

A unique question-and-answer book for surgical residents and trainees that covers all surgical aspects of critical care and acute or emergency medicine. This is a comprehensive, one-of-a-kind question-and-answer text for... read more

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients

The goal of this retrospective study was to investigate the effects of perioperative use of dexmedetomidine (Dex) on outcomes for older patients undergoing cardiac surgery. A total of 505 patients (equal or greater than 65... read more

The Association Between Visiting Intensivists and ICU Outcomes

The Association Between Visiting Intensivists and ICU Outcomes

During a period of service reconfiguration, intensivists routinely rostered to work in one ICU worked in another of the hospital's four ICUs. "Home" intensivists were those who continued to work in their usual... read more

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU

A restrictive transfusion threshold is recommended in nearly all critically ill patients. This is at least noninferior to more liberal transfusion practice; in addition, a restrictive threshold has shown improved outcomes... read more

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections

Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections

In this randomized, clinical pilot trial of patients undergoing emergency surgery for thoracic aorta dissections, we found that OctaplasLG reduced glycocalyx and endothelial injury, reduced bleeding, transfusions, use of... read more

Incidence, Severity, and Detection of Blood Pressure Perturbations after Abdominal Surgery

Incidence, Severity, and Detection of Blood Pressure Perturbations after Abdominal Surgery

Intraoperative and postoperative hypotension are associated with myocardial and kidney injury and 30-day mortality. Intraoperative blood pressure is measured frequently, but blood pressure on surgical wards is usually measured... read more

This Minimally Invasive Technique Could Reduce the Need for Open-Heart Surgery

This Minimally Invasive Technique Could Reduce the Need for Open-Heart Surgery

Currently, the majority of individuals who undergo transcather aortic valve replacement (TAVR), a minimally invasive alternative to open-heart surgery—are elderly or subject to compounding complications such as kidney disease.... read more

Extravascular Lung Water as a Target for Intensive Care

Extravascular Lung Water as a Target for Intensive Care

Extravascular lung water (EVLW) remains a useful guide for monitoring pulmonary edema (PO) and vascular permeability in sepsis, acute respiratory distress syndrome (ARDS), and heart failure. In addition, EVLW has a prognostic... read more

Trauma Electives in South Africa Provide Valuable Training for International Surgeons

Trauma Electives in South Africa Provide Valuable Training for International Surgeons

Trauma training and trauma preparedness are increasingly areas of concern worldwide. Formal military conflicts over the past 2 decades have ensured that most military surgeons have been exposed to a significant volume of... read more