Tag: therapy
Antibiotic therapy advances in the critically ill
Key issues related to antibiotic management in the critically ill, including problems associated with timing, duration, and dosing of antibiotics. The authors highlighted the importance of early diagnosis of infection and... read more
Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling
The researchers found that the drugs were well tolerated, with no serious adverse events reported. The indexed left ventricular end diastolic volume increased in patients treated with perindopril, bisoprolol, and placebo... read more
Warding off Fight, Flight, or Freeze
There's some evidence that suggests that just by telling people the physiological facts about stress, this is why you get tunnel vision, this is why you can't remember drug doses or what's next in the algorithm... read more
Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History
Having a history of cancer does not worsen outcomes for patients with STEMI who undergo primary PCI and should not be a barrier to revascularization and optimal therapy.... read more
Targeted Drug Delivery using Porous Glass Microspheres
Finding ways to improve efficiency and bioavailability is key to targeted drug delivery. Although controlled release dosage medication forms are the standard, they can have certain limitations.... read more
Negative pressure irrigation and endoscopic necrosectomy through man-made sinus tract in infected necrotizing pancreatitis
This four-step approach is effective in treating IPN and adds no extra risk to patients when compared with other latest step-up strategies. The two novel techniques (NPI and ED) could offer distinct clinical benefits without... read more
Combined Data Show Superiority of LAMA/LABA in COPD
Patients with chronic obstructive pulmonary disease (COPD) experienced significantly fewer acute exacerbations when a long-acting muscarinic antagonist (LAMA) was added to a long-acting beta agonist (LABA) than when an inhaled... read more
New Cytokine Approach is Synergistic With Checkpoint Inhibitors
Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more
Nonadherence to Meds Hurts NSTEMI Patients, Especially After PCI
Patients who were revascularized for a non-ST-segment elevation myocardial infarction (NSTEMI) did better if they adhered to their medications.... read more
One-Third of Hypertension Patients Noncompliant with Therapy
More than 30% of patients with hypertension do not adhere to their antihypertensive drug therapy, according to a new study.... read more
FDA Approves Defibrillator That Automatically Adjusts Pacing
The FDA has cleared the Claria MRI Quad Cardiac Resynchronization Therapy Defibrillator (CRT-D) SureScan device (Medtronic) for patients with heart failure.... read more
Bariatric surgery may protect against heart failure
Bariatric surgery appears to reduce substantially the risk of heart failure.... read more
Bacteriophages cure bacterial infections
Phage therapy may be a solution to treating infections caused by antibiotic-resistant bacteria. Since 2013, researchers at the University of Helsinki in Finland have collected bacteriophages to combat antibiotic-resistant... read more
PCSK9 Inhibition and Other New Therapies for Lipid Modification: Good News and Bad
A late-breaking clinical trial session devoted to newly approved and investigational compounds for the treatment of lipids highlighted the end of a once promising therapy for low HDL cholesterol.... read more
FDA Approves Carnexiv Injection for Seizures
The FDA has approved Carnexiv (carbamazepine) injection as a short-term replacement therapy for oral carbamazepine formulations for adults with certain seizure types.... read more
Guidelines for Neuromuscular Blockade in the Adult Critically Ill Patient
The Society of Critical Care Medicine recently released guidelines addressing sustained neuromuscular blockade in the adult critically ill patient.... read more
FDA to radiologists: stop using any Multidata Systems devices
At least two devices distributed in U.S. without FDA approval. There have been at least two Multidata medical devices that the company manufactured and distributed in the United States for which FDA never received nor reviewed... read more
5 New Oral Anticoagulants for Atrial Fibrillation
When trying to decide which therapy for nonvalvular atrial fibrillation (NVAF) is optimal for patients, many factors should be considered, including compliance, ability to perform daily activities of living, and nutrition... read more
Conservative oxygen treatment linked to lower ICU mortality
A conservative protocol for oxygen therapy results in lower intensive care unit (ICU) mortality compared to conventional care.... read more
New HIV treatment appears to have fully erased the virus from a patient's blood
A pioneering new trial offers new hope in the fight against HIV after a patient treated with a new therapy appears to have no trace of the virus in their blood.... read more
Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge
Over a recent 10-year period, there has been an improvement in the prescription of evidence-based medical therapy for patients who survive and are discharged from hospital after an MI, a new analysis shows.... read more
Association of Sodium Selenite and Procalcitonin-Guided Therapy With Mortality
This randomized clinical trial evaluates the use of high-dose sodium selenite, with or without use of a procalcitonin algorithm to guide therapy, and its association with mortality in patients with severe sepsis.... read more
