Evidence-Based Critical Care: A Case Study Approach

This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion... read more

Evidence-Based Critical Care: A Case Study Approach

Ketamine Can Be a Transformational Agent But Not Without Risk or Danger

Ketamine is growing as a tool in the world of emergency medicine, offering a broad spectrum of applications that underscore its pivotal role in modern therapeutic regimens. It is increasingly being recognized for its... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy Efficacy for the Management of Sepsis and Septic Shock

In this systematic review, we found that hydrocortisone, ascorbic acid, and thiamine (HAT) regimen may be useful for reducing the duration of vasopressor use and improve organ functions in patients with sepsis and septic... read more

Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

This case-series shows that a properly trained regular Helicopter Emergency Medical Services (HEMS) crew of only two health care professionals (doctor and flight nurse) can establish Extracorporeal-Cardiopulmonary Resuscitation... read more

Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

ECLS in Infarct-Related Cardiogenic Shock

In patients with acute myocardial infarction complicated by cardiogenic shock with planned early revascularization, the risk of death from any cause at the 30-day follow-up was not lower among the patients who received ECLS... read more

ECLS in Infarct-Related Cardiogenic Shock

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

The use of pressors and dilators are common in intensive care units, especially concerning the heart. With different mechanisms of action and titrations, it is essential to know how each of the drugs perform and the potential... read more

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

Novel Vasopressor Agent Adoption in Critically Ill Adults

This study aimed to investigate the utilisation of ATII in critically ill adults undergoing vasopressor therapy. The study included patients admitted to ICUs from January 1, 2018, to December 31, 2020, who received intravenous... read more

Novel Vasopressor Agent Adoption in Critically Ill Adults

Renal Replacement Therapy: Controversies and Future Trends

Controversies and trends have always been present in nephrology. Since its inception and throughout its development, renal replacement therapy has been shrouded in uncertainty, even as it advances, and it has always been... read more

Renal Replacement Therapy: Controversies and Future Trends

ReddyPort Non-Invasive Ventilation Device Cleared By FDA

ReddyPort announced today that the US Food and Drug Administration (FDA) granted 510(k) premarket clearance for the ReddyPort elbow device used in non-invasive ventilation (NIV). "ReddyPort's patented elbow is central... read more

ReddyPort Non-Invasive Ventilation Device Cleared By FDA

Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema

To determine whether a new surgical method using a flexible endoscope (FlexVATS) to perform sparing debridement and apply negative-pressure therapy without extensive decortication may be an alternative treatment option for... read more

Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Oxford Textbook of Critical Care

The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more

Oxford Textbook of Critical Care

Antifungal Stewardship in Critically Ill Patients

Antifungal stewardship (AFS) can improve performance measures and decrease antifungal consumption, with no negative impact on outcomes. β-D-glucan (BDG) are helpful to stop unnecessary treatment in patients with IC,... read more

Antifungal Stewardship in Critically Ill Patients

Acid-Base Disorders in the Critically III Patient

Acid-base disorders are common in the intensive care unit. By utilizing a systematic approach to their diagnosis, it is easy to identify both simple and mixed disturbances. These disorders are divided into four major categories:... read more

Acid-Base Disorders in the Critically III Patient

Clinical Applications of Magnets on Cardiac Rhythm Management Devices

The growing indications for permanent pacemaker and implantable cardioverter defibrillator (ICD) implantation have increased the number of patients with these cardiac rhythm management devices (CRMDs). Cardiac rhythm... read more

Clinical Applications of Magnets on Cardiac Rhythm Management Devices

Perioperative Management of Antithrombotic Therapy

Substantial new evidence has emerged since the 2012 iteration of these guidelines, especially to inform best practices for the perioperative management of patients who are receiving a VKA and may require heparin bridging,... read more

Perioperative Management of Antithrombotic Therapy

Subphenotypes of AKI in Adults

Subphenotyping may help reduce heterogeneity under the umbrella term of acute kidney injury (AKI). Despite challenges remain, the identification of AKI subphenotypes has opened the potential of AKI research focused on better... read more

Subphenotypes of AKI in Adults

Surfactant Therapies for Pediatric ARDS

We advocate for well-designed preclinical and explanatory clinical studies to investigate the use of surfactant for pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome. Given the accumulating knowledge... read more

Surfactant Therapies for Pediatric ARDS

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental... read more

Prevalence of PICS in Mechanically Ventilated Patients with COVID-19

Closed-loop oxygen control improves oxygen therapy in AHRF patients under high flow nasal oxygen

Closed-loop oxygen control improves oxygen administration in patients with moderate-to-severe AHRF treated with HFNO, increasing the percentage of time in the optimal oxygenation range and decreasing the workload of healthcare... read more

Closed-loop oxygen control improves oxygen therapy in AHRF patients under high flow nasal oxygen

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19

Among critically ill patients with COVID-19, treatment with an antiplatelet agent, compared with no antiplatelet agent, had a low likelihood of providing improvement in the number of organ support–free days within 21 days. The... read more

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19