Tag: therapy
Verticalization Therapy for ARDS Patients Receiving VV-ECMO
Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more
Oxford Textbook of Critical Care
The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more
Antifungal Stewardship in Critically Ill Patients
Antifungal stewardship (AFS) can improve performance measures and decrease antifungal consumption, with no negative impact on outcomes. β-D-glucan (BDG) are helpful to stop unnecessary treatment in patients with IC,... read more
Acid-Base Disorders in the Critically III Patient
Acid-base disorders are common in the intensive care unit. By utilizing a systematic approach to their diagnosis, it is easy to identify both simple and mixed disturbances. These disorders are divided into four major categories:... read more
Clinical Applications of Magnets on Cardiac Rhythm Management Devices
The growing indications for permanent pacemaker and implantable cardioverter defibrillator (ICD) implantation have increased the number of patients with these cardiac rhythm management devices (CRMDs). Cardiac rhythm... read more
Perioperative Management of Antithrombotic Therapy
Substantial new evidence has emerged since the 2012 iteration of these guidelines, especially to inform best practices for the perioperative management of patients who are receiving a VKA and may require heparin bridging,... read more
Subphenotypes of AKI in Adults
Subphenotyping may help reduce heterogeneity under the umbrella term of acute kidney injury (AKI). Despite challenges remain, the identification of AKI subphenotypes has opened the potential of AKI research focused on better... read more
Surfactant Therapies for Pediatric ARDS
We advocate for well-designed preclinical and explanatory clinical studies to investigate the use of surfactant for pediatric (PARDS) and neonatal (NARDS) acute respiratory distress syndrome. Given the accumulating knowledge... read more
Prevalence of PICS in Mechanically Ventilated Patients with COVID-19
Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental... read more
Closed-loop oxygen control improves oxygen therapy in AHRF patients under high flow nasal oxygen
Closed-loop oxygen control improves oxygen administration in patients with moderate-to-severe AHRF treated with HFNO, increasing the percentage of time in the optimal oxygenation range and decreasing the workload of healthcare... read more
Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19
Among critically ill patients with COVID-19, treatment with an antiplatelet agent, compared with no antiplatelet agent, had a low likelihood of providing improvement in the number of organ support–free days within 21 days. The... read more
Prevalence of COVID-19-Associated Pulmonary Aspergillosis
First reports of cases and case series of COVID-19-associated pulmonary aspergillosis (CAPA) emerged during the first months of the pandemic. Prevalence rates varied widely due to the fact that CAPA was, and still remains,... read more
Music Therapy Intervention to Treat Sedation-Related Delirium in Critical Care
Sedation is an essential component of treatment for some patients admitted to the intensive care unit, but it carries a risk of sedation-related delirium. Sedation-related delirium is associated with higher mortality and... read more
Obstructive Airway Diseases: Role of Lipid Mediators
Incidences of inflammatory airway diseases are on the rise across the world. Existing therapeutic options are ineffective, unsafe, and expensive, and severe cases are nonresponsive to conventional therapy. Therefore, it is... read more
Association Between Dexamethasone Treatment for COVID-19 Patients and Rates of Hospital Readmission and Mortality
Current guidelines recommend use of dexamethasone, 6 mg/d, up to 10 days or until discharge for patients hospitalized with COVID-19. Whether patients who received less than 10 days of corticosteroids during hospitalization... read more
Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema
This study compared the effect of placebo versus the bradykinin B2 receptor antagonist icatibant on symptoms of ACE inhibitor–associated angioedema in a mixed race population of patients. The study does not support the... read more
Balanced vs. Unbalanced Fluid in Critically Ill Children
Our systematic review found some evidence of improvement in blood pH and bicarbonate values in critically ill children after 4–12 hours of fluid bolus therapy with balanced fluid compared with the unbalanced fluid. However,... read more
