Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients

Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

Therapeutic Hypothermia After Cardiac Arrest

Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated.... read more

Therapeutic Hypothermia After Cardiac Arrest

CAR-T Therapy – Critical Care Considerations of Chimeric Antigen Receptor

Despite significantly improving the treatment of blood cancers, CAR T-cell therapy still faces significant hurdles due to its complex and varied toxicities, which require ongoing research to optimize management; while understanding... read more

Cellular Therapy with Mesenchymal Stromal Cells in Sepsis

Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more

Impact of Time to Catheter-Based Therapy on Outcomes in Acute Pulmonary Embolism

Early catheter-based therapie (CBT) was associated with improved clinical outcomes in patients with acute intermediate-risk pulmonary embolism (PE). The composite PE shock score may help identify patients who will benefit... read more

Therapy Dogs Aren’t Just for Patients

My hospital brought in a therapy dog for our ED team after a critical incident stress debriefing (CISD). I had never received dog therapy before. The big eyes and loving licks on our hands honestly helped. Perhaps what... read more

Personalized Therapies in ARDS

Acute respiratory distress syndrome (ARDS) can result from a variety of clinical conditions, causing lung injury either directly through local inflammation or indirectly because of systemic inflammatory mediators ARDS is... read more

Protocolized Fluid Balance Neutralization During CRRT

Bitker et al. report the GO NEUTRAL randomized clinical trial results, which investigated fluid balance neutralization guided by functional hemodynamic monitoring (FHM) protocol versus a standard of care in critically ill... read more

Evidence-Based Critical Care: A Case Study Approach

This book provides learners with a unique opportunity by virtue of the format outlined above. Each case presentation has a case vignette, which leads up to an important clinical question, and is followed by additional discussion... read more

Evidence-Based Critical Care: A Case Study Approach

Ketamine Can Be a Transformational Agent But Not Without Risk or Danger

Ketamine is growing as a tool in the world of emergency medicine, offering a broad spectrum of applications that underscore its pivotal role in modern therapeutic regimens. It is increasingly being recognized for its... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more

Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice

Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy Efficacy for the Management of Sepsis and Septic Shock

In this systematic review, we found that hydrocortisone, ascorbic acid, and thiamine (HAT) regimen may be useful for reducing the duration of vasopressor use and improve organ functions in patients with sepsis and septic... read more

Feasibility of HEMS Performed Prehospital E-CPR in Pediatric Cardiac Arrests

This case-series shows that a properly trained regular Helicopter Emergency Medical Services (HEMS) crew of only two health care professionals (doctor and flight nurse) can establish Extracorporeal-Cardiopulmonary Resuscitation... read more

ECLS in Infarct-Related Cardiogenic Shock

In patients with acute myocardial infarction complicated by cardiogenic shock with planned early revascularization, the risk of death from any cause at the 30-day follow-up was not lower among the patients who received ECLS... read more

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

The use of pressors and dilators are common in intensive care units, especially concerning the heart. With different mechanisms of action and titrations, it is essential to know how each of the drugs perform and the potential... read more

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

Novel Vasopressor Agent Adoption in Critically Ill Adults

This study aimed to investigate the utilisation of ATII in critically ill adults undergoing vasopressor therapy. The study included patients admitted to ICUs from January 1, 2018, to December 31, 2020, who received intravenous... read more

Renal Replacement Therapy: Controversies and Future Trends

Controversies and trends have always been present in nephrology. Since its inception and throughout its development, renal replacement therapy has been shrouded in uncertainty, even as it advances, and it has always been... read more

Renal Replacement Therapy: Controversies and Future Trends

ReddyPort Non-Invasive Ventilation Device Cleared By FDA

ReddyPort announced today that the US Food and Drug Administration (FDA) granted 510(k) premarket clearance for the ReddyPort elbow device used in non-invasive ventilation (NIV). "ReddyPort's patented elbow is central... read more

Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema

To determine whether a new surgical method using a flexible endoscope (FlexVATS) to perform sparing debridement and apply negative-pressure therapy without extensive decortication may be an alternative treatment option for... read more

Verticalization Therapy for ARDS Patients Receiving VV-ECMO

Persistent hypoxemia during veno-venous extracorporeal membrane oxygenation (VV-ECMO) for supporting acute respiratory distress syndrome (ARDS) patients is a clinical challenge for intensive care medical providers. Prone... read more

Oxford Textbook of Critical Care

The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more

Oxford Textbook of Critical Care