Tag: therapy
PCSK9 Inhibition and Other New Therapies for Lipid Modification: Good News and Bad
A late-breaking clinical trial session devoted to newly approved and investigational compounds for the treatment of lipids highlighted the end of a once promising therapy for low HDL cholesterol.... read more
FDA Approves Carnexiv Injection for Seizures
The FDA has approved Carnexiv (carbamazepine) injection as a short-term replacement therapy for oral carbamazepine formulations for adults with certain seizure types.... read more
Guidelines for Neuromuscular Blockade in the Adult Critically Ill Patient
The Society of Critical Care Medicine recently released guidelines addressing sustained neuromuscular blockade in the adult critically ill patient.... read more
FDA to radiologists: stop using any Multidata Systems devices
At least two devices distributed in U.S. without FDA approval. There have been at least two Multidata medical devices that the company manufactured and distributed in the United States for which FDA never received nor reviewed... read more
5 New Oral Anticoagulants for Atrial Fibrillation
When trying to decide which therapy for nonvalvular atrial fibrillation (NVAF) is optimal for patients, many factors should be considered, including compliance, ability to perform daily activities of living, and nutrition... read more
Conservative oxygen treatment linked to lower ICU mortality
A conservative protocol for oxygen therapy results in lower intensive care unit (ICU) mortality compared to conventional care.... read more
New HIV treatment appears to have fully erased the virus from a patient's blood
A pioneering new trial offers new hope in the fight against HIV after a patient treated with a new therapy appears to have no trace of the virus in their blood.... read more
Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge
Over a recent 10-year period, there has been an improvement in the prescription of evidence-based medical therapy for patients who survive and are discharged from hospital after an MI, a new analysis shows.... read more
Association of Sodium Selenite and Procalcitonin-Guided Therapy With Mortality
This randomized clinical trial evaluates the use of high-dose sodium selenite, with or without use of a procalcitonin algorithm to guide therapy, and its association with mortality in patients with severe sepsis.... read more
Gene therapy for LPLD patients linked to lower frequency and severity of pancreatitis
Up to 6 years after receiving a single treatment with the gene therapy product lipoprotein lipase (LPL), patients with the debilitating genetic disease LPL deficiency (LPLD) had about 50% fewer episodes of pancreatitis than... read more
ICDs appear not to improve overall survival in non-ischemic systolic HF
This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more
Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke
Compared to patients treated with medical therapy alone, patients with an ischemic stroke undergoing endovascular thrombectomy combined with medical therapy had lower rates of disability 3 months after their stroke.... read more
Alcohol Withdrawal Syndrome
Alcohol withdrawal syndrome (AWS) is present in 20% of all hospital admissions and contributes to at least 30% of critical care admissions.1 Patients who develop AWS require longer hospitalizations and have extensive medical... read more
Catheter ablation more effective than antiarrythmic escalation
Catheter ablation was found to be more effective than escalated antiarrhythmic drug (AAD) therapy at treating patients with ischemic cardiomyopathy and an implantable cardioverter-defibrillator (ICD) who had ventricular tachycardia... read more
Decompressive craniectomy linked with decreased mortality in TBI
Patients with traumatic brain injury (TBI) and refractory intracranial hypertension following 2 stages of standard therapy who were then randomized to receive decompressive craniectomy had lower rates of mortality and higher... read more
Review: Stem Cell Tx for Heart Failure Not Ready Yet
Heterogeneity in methods for trials of stem cell therapies for heart failure are a big reason for the inconsistent results seen to date, a review article suggested.... read more
Earlier Renal Replacement Therapy for AKI? Not So Fast, Says Dr Berns
The AKIKI study was published in the New England Journal of Medicine; ELAIN was published in JAMA. If you have not read them, you should, if for no other reason than that your colleagues are likely to ask about them.... read more
