Tag: treatment
Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device
This study demonstrated the performance of the SAME device. Platelets and red blood cells were salvaged without significant impact on cell integrity and function. In the meantime, leukocytes were not activated, and the washing... read more
Low Technology, Mild Controlled Hypothermia for Necrotizing Enterocolitis Treatment
Low technology, mild controlled hypothermia was feasible, not related to adverse effects, and effective treatment for NEC Modified Bell's Stage II/III. It avoided surgery, bowel perforation, and extensive intestinal resection;... read more
Oral Midodrine Feasibility in Early Sepsis
This study proved the feasibility of clinical trial to use oral midodrine in early sepsis. The study was not powered to detect statistically significant differences between the two groups, and therefore, the results from... read more
Guidance on COVID-19 Clinical Care and Treatment by Specialty
We are providing these links as part of our support to members seeking specialty advice for specific medical conditions, particularly those outside their own specialty. The situation is a fast-evolving one, and while we will... read more
New Therapy Could Protect Lung Function in COVID-19 Patients
There is an urgent need for new drugs for ARDS patients, including those with COVID-19. ARDS in influenza-infected mice is associated with reduced levels of liponucleotides (essential precursors for de novo phospholipid synthesis)... read more
Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment
Referral to specialized center for venovenous (VV) ECMO treatment should be considered expeditiously in case of refractory ARDS, which is often lethal. Transport of unstable patients, although challenging, is feasible and... read more
Mythbusting: (Empty IVC + Hyperkinetic Heart) Does Not Equal Volume Depletion
An empty IVC and hyperkinetic heart does not equal volume depletion. This combination of echocardiographic findings may result from either vasodilatory shock (as illustrated above) or hypovolemic shock. If encountered in... read more
Remestemcel-L reduces ARDS mortality in those under 65 years old
New data shows patients with COVID-19-related Acute Respiratory Distress Syndrome (ARDS) were up to 75 percent less likely to die when treated with remestemcel-L and dexamethasone. The data shows remestemcel-L reduced... read more
POCUS of the Heart and Lungs in Patients with Respiratory Failure
Point-of-care ultrasound (POCUS) is a focus oriented tool for differentiating among cardiopulmonary diseases. Its value in the hands of emergency physicians, with various ultrasound experience, remains uncertain. We tested... read more
Decreased Mortality in ARDS Patients Treated with Corticosteroids
The use of glucocorticoids might result in reduced mortality in patients with ARDS. Glucocorticoids might be recommended as an adjunct to standard care for ARDS; however, the optimal dose and duration of steroid therapy remains... read more
Cytokine Adsorption Effect on Survival and Circulatory Stabilization in Patients Receiving ECPR
Even after the introduction of extracorporeal cardiopulmonary resuscitation (ECPR), survival after cardiac arrest remains poor. Excess release of vasoactive cytokines may be a reason for cardiovascular instability and death... read more
Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins
A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure. The trial... read more
Validation of Sputum Gram Stain for Treatment of CAP and HCAP
The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more
Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid
Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics... read more
Patient’s Clinical Presentation and CPPopt Availability: Any Association?
In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more
Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients
Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more
Peripheral Arteriovenous Malformations: Classification and Endovascular Treatment
In this review we cover the classification and endovascular management of arteriovenous malformations (AVMs). We begin by viewing AVMs in relation to the broader class of congenital vascular malformations and subsequently... read more
Operative Techniques and Recent Advances in Acute Care and Emergency Surgery
The aim of this book is to identify and shed new light on the main surgical practices involved in acute care and trauma surgery. Adopting an evidence-based approach, a multidisciplinary team of surgeons and intensivists... read more
Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments
In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more
Mayo Clinic Critical and Neurocritical Care Board Review
Mayo Clinic Critical and Neurocritical Care Board Review is an all-inclusive review of the pathophysiology and care of the neurocritically ill and critically ill patient. The book reviews the core major critical care... read more
Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock
PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more
