FDA to radiologists: stop using any Multidata Systems devices

FDA to radiologists: stop using any Multidata Systems devices

At least two devices distributed in U.S. without FDA approval. There have been at least two Multidata medical devices that the company manufactured and distributed in the United States for which FDA never received nor reviewed... read more

FDA Approves Zinplava to Reduce Recurrence of Clostridium difficile Infection in Adult Patients

FDA Approves Zinplava to Reduce Recurrence of Clostridium difficile Infection in Adult Patients

FDA Approves Merck's ZINPLAVA (bezlotoxumab) to Reduce Recurrence of Clostridium difficile Infection (CDI) in Adult Patients Receiving Antibacterial Drug Treatment for CDI Who Are at High Risk of CDI Recurrence.... read more

Inappropriate Antibiotic Selection Among US Ambulatory Care Visits

Inappropriate Antibiotic Selection Among US Ambulatory Care Visits

This study measures the frequency with which first-line antibiotics are prescribed for otitis media, sinusitis, and pharyngitis.... read more

FDA Approves sNDA for Label Changes to ADASUVE

FDA Approves sNDA for Label Changes to ADASUVE

The FDA has approved the supplemental New Drug Application for label changes to ADASUVE (loxapine) inhalation powder. ADASUVE is the first orally inhaled medication for the acute treatment of agitation associated with bipolar... read more

Cartilage From Nose Used to Repair Bum Knees

Cartilage From Nose Used to Repair Bum Knees

Using cells from the cartilage in patients' noses, Swiss doctors have successfully made patches to treat 10 adults whose knee cartilage was damaged by injury.... read more

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA has released a new scientific statement for managing clinically significant drug-drug interactions in patients who are prescribed statins and other agents used in the treatment of cardiovascular disease.... read more

Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis

Successful treatment with fecal microbiota transplantation in patients with multiple organ dysfunction syndrome and diarrhea following severe sepsis

The outcome of treating two patients with FMT indicates that restoration of the intestinal microbiota barrier can alleviate the infection and modulate the immune response.... read more

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more

Neuropilin 2 deficiency linked to inflammation-induced edema

Neuropilin 2 deficiency linked to inflammation-induced edema

A deficiency in neuropilin 2 receptors may result in prolonged fluid buildup after inflammation, researchers found in a study on edema and lymphedema.... read more

Targeted thyroid hormone delivery reduces off-target effects

Targeted thyroid hormone delivery reduces off-target effects

This work provides strong evidence that targeted delivery of T3 via hybridization to glucagon can be a potent treatment option for metabolic syndrome and associated diseases.... read more

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

Levosimendan Doesn’t Prevent Acute Organ Dysfunction

For adults with sepsis, levosimendan does not prevent acute organ dysfunction.... read more

Conservative oxygen treatment linked to lower ICU mortality

Conservative oxygen treatment linked to lower ICU mortality

A conservative protocol for oxygen therapy results in lower intensive care unit (ICU) mortality compared to conventional care.... read more

Empirical micafungin treatment doesn't improve survival

Empirical micafungin treatment doesn't improve survival

Empirical treatment with micafungin seems not to increase invasive fungal infection (IFI)-free survival at 28 days for patients with intensive care unit (ICU)-acquired sepsis with Candida colonization.... read more

FDA Warns About Hepatitis B Reactivation from Hepatitis C Antivirals

FDA Warns About Hepatitis B Reactivation from Hepatitis C Antivirals

The FDA issued a warning yesterday about the risk of hepatitis B virus becoming active again in patients with current or previous infection who received treatment with hepatitis C virus treatments.... read more

New HIV treatment appears to have fully erased the virus from a patient's blood

New HIV treatment appears to have fully erased the virus from a patient's blood

A pioneering new trial offers new hope in the fight against HIV after a patient treated with a new therapy appears to have no trace of the virus in their blood.... read more

New tool helps measure how costs of care impact cancer patients

New tool helps measure how costs of care impact cancer patients

For many patients, the uncertainty and stress that can come with cancer treatment is compounded by what is now known as "financial toxicity", the anxiety and distress that follow health care and medication expenses, often... read more

Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge

Use of Evidence-Based Medical Therapy Steadily Improving in Acute MI Patients Postdischarge

Over a recent 10-year period, there has been an improvement in the prescription of evidence-based medical therapy for patients who survive and are discharged from hospital after an MI, a new analysis shows.... read more