Tag: trial
Hydrocortisone and Septic Shock in Patients With Severe Sepsis
This randomized clinical trial compares the effects of hydrocortisone vs placebo on development of septic shock among intensive care patients with severe sepsis who were not in septic shock.... read more
Transcranial direct current stimulation enhances cognitive training in Parkinson’s
Transcranial direct current stimulation plus cognitive training may produce the best cognitive results in Parkinson’s patients with mild cognitive impairment. tDCS adds cognitive benefit when combined with cognitive training... read more
Glycemic control, mortality, and hypoglycemia in critically ill patients: a systematic review and network meta-analysis of randomized controlled trials
Network meta-analysis showed no mortality benefit of tight glycemic control in critically ill patients, but fivefold more hypoglycemia versus mild or very mild control.... read more
Association of Sodium Selenite and Procalcitonin-Guided Therapy With Mortality
This randomized clinical trial evaluates the use of high-dose sodium selenite, with or without use of a procalcitonin algorithm to guide therapy, and its association with mortality in patients with severe sepsis.... read more
ICDs appear not to improve overall survival in non-ischemic systolic HF
This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more
Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke
Compared to patients treated with medical therapy alone, patients with an ischemic stroke undergoing endovascular thrombectomy combined with medical therapy had lower rates of disability 3 months after their stroke.... read more
Beta-Lactam Infusion in Severe Sepsis (BLISS)
Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.... read more
FDA approves automated insulin delivery device for type 1 diabetes
The Food and Drug Administration (FDA) has approved a device that automatically monitors blood glucose levels and delivers insulin when appropriate, for people aged 14 years and older who have type 1 diabetes.... read more
When Your Doctor Is on a 30-Hour Shift
A new program has medical residents working for up to 30 hours without sleep in ICUs - putting patients in danger of hospital errors.... read more
Dramatic remissions seen in immunotherapy trial of blood cancer patients
Many patients with advanced blood cancers who are receiving experimental, "living" immunotherapy as part of a clinical trial are experiencing sustained remissions, according to preliminary results of the ongoing... read more
Researchers hope to speed recovery of critically ill patients with bikes in their beds
An experiment in the intensive care unit of The Ottawa Hospital aims to test whether critically ill patients can get back on their feet faster by cycling in bed. As part of the randomized clinical.... read more
New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients
Astute Medical, Inc., developer of biomarkers for better healthcare, today said that newly published findings show that the Company's NEPHROCHECK Test may help physicians identify risk of a serious complication in patients... read more
Signs of Cardioprotection Seen in Acute STEMI Patients Receiving IV Beta-blocker Post-PCI
Patients with STEMI who receive IV infusion of the beta-blocker esmolol within 60 minutes after successful PCI tend to release smaller amounts of cardiac biomarkers than those given placebo, researchers of a single-center,... read more
Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery
Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have the potential to reduce acute kidney injury (AKI) after cardiac surgery through their pleiotropic properties. Here we studied the preventive... read more
Catheter ablation more effective than antiarrythmic escalation
Catheter ablation was found to be more effective than escalated antiarrhythmic drug (AAD) therapy at treating patients with ischemic cardiomyopathy and an implantable cardioverter-defibrillator (ICD) who had ventricular tachycardia... read more
