Conservative or Liberal Oxygen Targets in Patients on VA-ECMO

In adults receiving VA-ECMO in the ICU, a conservative compared to a liberal oxygen strategy did not affect the number of ICU-free days to day 28, nor any other measurable patient outcomes up to 6 months after ICU admission.... read more

Vasoconstriction in Septic Shock

Septic shock is associated with endothelial dysfunction leading to arterial and venous dilation, alterations in regional blood flow distribution, and microcirculatory disturbances. Fluids and vasopressors are the key... read more

Methylene Blue in Sepsis and Septic Shock

Methylene Blue in Sepsis and Septic Shock

This systematic review and meta-analysis evaluated the effect of MB in three RCTs. They found that MB treatment significantly reduced time to vasopressor discontinuation, days on mechanical ventilation, and length of ICU... read more