Tag: ventilation
The PreVent Trial, Assessing the Role of Bag-mask Ventilation During Tracheal Intubation in Critically Ill Adults
In this "Breathe Easy Critical Perspective" podcast, Dr. Dominique Pepper interviews Dr. Matthew Semler. They discuss the PreVent trial, a recent publication in the 2019 issue of the NEJM that assessed the role of bag-mask... read more
Muscle Atrophy in Mechanically-ventilated Critically Ill Children
In children receiving invasive mechanical ventilation, diaphragm and other skeletal muscle atrophy is common and rapid. Increasing age and TBI may increase severity of limb muscle atrophy. Prospective studies are required... read more
ICU Utilization for Patients With Acute Exacerbation of COPD Receiving Noninvasive Ventilation
There is wide variability in the rate of ICU utilization for noninvasive ventilation across hospitals. Chronic obstructive pulmonary disease (COPD) patients receiving noninvasive ventilation had similar in-hospital mortality... read more
DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not... read more
Effect of high-flow nasal cannula oxygen therapy in adults with acute hypoxemic respiratory failure
Conflicting recommendations exist on whether high-flow nasal cannula (HFNC) oxygen therapy should be administered to adult patients in critical care with acute hypoxemic respiratory failure. We performed a meta-analysis of... read more
One of the Deadliest Hospital-Acquired Infections Is Preventable
Johns Hopkins Study Shows One of the Deadliest Hospital-Acquired Infections Is Preventable. For some hospital patients, going on a ventilator is often the difference between life and death. About 800,000 hospital patients... read more
High-frequency Oscillatory Ventilation: Still a Role?
In light of emerging data from clinical trials, the place of high-frequency oscillatory ventilation (HFOV) in the management of acute respiratory distress syndrome (ARDS) is uncertain. Although not first-line, HFOV remains... read more
Relationship Between Level of CPR Training, Self-reported Skills, and Actual Manikin Test Performance
As expected, higher levels of BLS training correlated with better cardiopulmonary resuscitation (CPR) quality. However, this study showed that ventilations and hands-on time were the components of CPR that were most affected... read more
Cricoid Pressure in Airway Management: The IRIS Trial
This large randomized clinical trial performed in patients undergoing anesthesia with RSI failed to demonstrate the non-inferiority of the sham procedure in preventing pulmonary aspiration. Further studies are required in... read more
The Benefit of Lung-Protective Ventilation in the ED
Intubation and mechanical ventilation are commonly performed ED interventions and although patients optimally go to an ICU level of care afterwards, many of them remain in the ED for prolonged periods of time. It is widely... read more
A Familiar Story: Delirium in the Acute Care Setting
A few years ago, I received report that a patient was ready to be weaned from the ventilator. He had no respiratory need for mechanical ventilation, and every time the medical team attempted to wean sedation to extubate,... read more
Prospective Assessment of the Feasibility of a Trial of Low Tidal Volume Ventilation for Patients with Acute Respiratory Failure
Use of initial tidal volumes less than 8 ml/kg PBW is common at hospitals participating in the NHLBI PETAL Network. After considering the size and budgetary requirement for a cluster-randomized trial of LTVV vs. usual care... read more
Decontaminants Don’t Cut Bloodstream Infection Risk in Ventilated ICU Patients
The use of digestive and oral decontaminants in patients in the intensive care unit (ICU) who are mechanically ventilated and who have moderate to high antibiotic resistance is not associated with a reduction in ICU-acquired... read more
Sedation and Neurodevelopmental Outcomes in PICU
As little as 30 minutes of exposure to anesthetic and sedative agents may adversely affect the developing brain. Safe, humane management of critically ill infants requires the use of sedative agents, often for prolonged periods.... read more
Critical Care Medicine: The Essentials and More
With a full-color design and concise, easy-to-read chapters, Critical Care Medicine: The Essentials and a Bit More covers the core elements of critical care, with a unique focus on the pathophysiology underlying clinical... read more
Effect of Bag-Mask Ventilation vs Endotracheal Intubation During CPR on Neurological Outcome After OHCA
Among patients with out-of-hospital cardiorespiratory arrest (OHCA), the use of BMV compared with ETI failed to demonstrate noninferiority or inferiority for survival with favorable 28-day neurological function, an inconclusive... read more
Impact of Drug and Equipment Preparation on Pre-hospital Emergency Anesthesia Procedural Time, Error Rate and Cognitive Load
Pre-preparation of Preparation on Pre-hospital Emergency (PHEA) equipment and drugs resulted in safer performance of PHEA and has the potential to reduce on-scene time by up to a third. In total 23 experiments were completed,... read more