Evaluating the Cost-Effectiveness of Proportional-Assist Ventilation Plus vs. Pressure Support Ventilation in the ICU in Two Countries

Evaluating the Cost-Effectiveness of Proportional-Assist Ventilation Plus vs. Pressure Support Ventilation in the ICU in Two Countries

The published reductions in asynchrony and length of stay in the ICU with proportional assist ventilation (PAV ventilation by Medtronic) led to shorter time on ventilation, and reduced incidence of ventilator-associated pneumonia... read more

The Role of Speech and Language Therapy in Critical Care

The Role of Speech and Language Therapy in Critical Care

The role of speech and language therapists (SLTs) in critical care can be unclear so this article sets out the scope of practice to increase awareness of the value of SLTs as part of the wider multidisciplinary team. Speech... read more

The Answer My Friend is Blowin’ in your Nose – High Flow Nasal Oxygen

The Answer My Friend is Blowin’ in your Nose – High Flow Nasal Oxygen

High flow nasal oxygen is a novel device that actively humidifies and heats air to make flows of up to 60 liters a minutes tolerable. These incredibly high flows are important, because in order to provide 100% fiO2 to patients... read more

Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children

Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children

Early noninvasive ventilation combined with nonroutine transfusion is well tolerated in acute chest syndrome in children and may spare transfusion in some patients. Early recognition of patients still requiring transfusion... read more

Oxygen: Savior or Devil in a Green Dress?

Oxygen: Savior or Devil in a Green Dress?

If you ask any small child what doctors do or what happens in a hospital, you'll probably get some variation of "they make sick people better." Were you to ask the same question of one of those doctors or someone working... read more

Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage

Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage

Trauma is a leading cause of death worldwide with 5.8 million deaths occurring yearly. Almost 40% of trauma deaths are due to bleeding and occur in the first few hours after injury. Of the remaining severely injured patients... read more

Limiting Sedation for Patients with ARDS

Limiting Sedation for Patients with ARDS

Current evidence supports the use of protocol-based, light-sedation strategies in critically ill patients with ARDS. Further research into sedation management specifically in ARDS populations is needed. Deep sedation strategies... read more

Advances in Critical Care Management of Patients Undergoing Cardiac Surgery

Advances in Critical Care Management of Patients Undergoing Cardiac Surgery

Cardiac surgery has been evolving to include minimally invasive, hybrid and transcatheter techniques. Increas‑ing patient age and medical complexity means that critical care management needs to adapt and evolve. Recent... read more

Mechanical Ventilation: Physiological and Clinical Applications

Mechanical Ventilation: Physiological and Clinical Applications

Known for its simple explanations and in-depth coverage of patient-ventilator management, this evidence-based text walks readers through the most fundamental and advanced concepts surrounding mechanical ventilation and guides... read more

The A1 Sedation Package: Better Care for Intubated Patients

The A1 Sedation Package: Better Care for Intubated Patients

You are called to the scene of a 56-year-old male found unresponsive in his garage workshop. Upon examining him you find him minimally responsive to painful stimulus, moaning and groaning. His family tells you he has high... read more

Fluid Bolus Over 15-20 Versus 5-10 Minutes Each in the First Hour of Resuscitation in Children With Septic Shock

Fluid Bolus Over 15-20 Versus 5-10 Minutes Each in the First Hour of Resuscitation in Children With Septic Shock

Children receiving fluid boluses over 5–10 minutes each had a higher risk of intubation than those receiving boluses over 15–20 minutes each. Notwithstanding the lack of difference in risk of mortality and the possibility... read more

Comparing Effects Between Music Intervention and Aromatherapy on Anxiety of Patients Undergoing Mechanical Ventilation in the ICU

Comparing Effects Between Music Intervention and Aromatherapy on Anxiety of Patients Undergoing Mechanical Ventilation in the ICU

Music and aromatherapy interventions were both effective for ICU patients. The effects of music intervention were greater than that of aromatherapy; both interventions maintained the effects for at least 30 min. The Music... read more

When to Withdraw Resuscitation in the ED

When can and should we withdraw from continuing resuscitation in the Emergency Department? We are here to save lives. I would argue the Emergency Medicine is a very pure expression of a Doctor's role: we meet a patient, we... read more

One-Year Outcomes in Patients With ARDS

One-Year Outcomes in Patients With ARDS

Poor functional recovery after invasive mechanical ventilation for acute respiratory distress syndrome is common. Helmet noninvasive ventilation may be the first intervention that mitigates the long-term complications that... read more

Adaptive servo ventilation cuts atrial fib burden

Adaptive servo ventilation cuts atrial fib burden

Adaptive servo ventilation produced a significant and clinically meaningful reduction in atrial fibrillation burden in patients with heart failure and sleep apnea in results from an exploratory, prospective, randomized study... read more

Intra-Abdominal Hypertension Is More Common Than Previously Thought

Intra-Abdominal Hypertension Is More Common Than Previously Thought

Intra-abdominal hypertension is common in both surgical and nonsurgical patients in the intensive care setting and was found to be independently associated with mortality. Despite prior reports to the contrary, intra-abdominal... read more

High-Flow Nasal Cannula in Critically Ill Subjects With or at Risk for Respiratory Failure

High-Flow Nasal Cannula in Critically Ill Subjects With or at Risk for Respiratory Failure

High-flow nasal cannula (HFNC) oxygen delivery has been gaining attention as an alternative means of respiratory support for critically ill patients, with recent studies suggesting equivalent outcomes when compared with other... read more