Urinary Source Saves Lives: Why Infection Origin Matters in Septic Shock for Patients Over 90

In critically ill nonagenarians and centenarians admitted to ICUs with septic shock, the source of infection emerges as a key independent predictor of long-term survival, varying over time. Patients with septic shock from... read more

Beyond the Basics: New Respiratory Markers Predict Extubation Failure

A multicenter study focused on high-risk patients who successfully passed a conventional 30-minute Spontaneous Breathing Trial (SBT) found that standard measures alone are insufficient to predict extubation failure. Extubation... read more

Monitoring Mechanical Ventilation Using Ventilator Waveforms

This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes... read more

Monitoring Mechanical Ventilation Using Ventilator Waveforms

Less Sedation, Shorter Stays: The Benefit of Analgesia-Based Protocols

A retrospective study conducted in a 24-bed medical Intensive Care Unit (ICU) compared patient outcomes before and after implementing a new analgesia-based sedation protocol. The research included 79 patients managed... read more

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

Ventilator Management: A Pre-Hospital Perspective

Critical Care Pearls: ICU Q&A Handbook for Critical Care Medicine: A Board Review and Daily Clinical Practice. Rapid Reference for Physicians, Fellows & Nurses

In the fast-paced world of intensive care medicine, every second counts and every question matters. Critical Care Pearls – Third Edition delivers over a thousand carefully curated ICU questions and evidence-based answers... read more

Critical Care Pearls: ICU Q&A Handbook for Critical Care Medicine: A Board Review and Daily Clinical Practice. Rapid Reference for Physicians, Fellows & Nurses

Restoring Voices: Safety and Success of In-Line Speaking Valves

A retrospective cohort study evaluated the safety and tolerability of placing a speaking valve directly in-line with the ventilator circuit for critically ill, tracheostomized patients who were difficult to wean from mechanical... read more

Mechanical Ventilation in Emergency Medicine

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more

Mechanical Ventilation in Emergency Medicine

Corticosteroids in ARDS: Delaying High-Dose Methylprednisolone Doesn’t Kill

This large retrospective study investigated whether starting high-dose (2 mg/kg) methylprednisolone therapy after 14 days of Acute Respiratory Distress Syndrome (ARDS) onset increased the risk of complications or mortality... read more

Voice Breakthrough: Bringing Speech Back to Ventilator Patients

This retrospective cohort study investigated the safety and success of placing a speaking valve in-line with the mechanical ventilator circuit for critically ill, tracheostomized patients who struggled to wean from the ventilator. Study... read more

Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

The new edition presents updates regarding new clinical applications of noninvasive mechanical ventilation and discusses recent technical advances in this field. The opening sections are devoted to theory, equipment, with... read more

Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

VAEs are Real: Advanced Modeling Confirms Ventilator Events Drive Worse Outcomes

The study by Nakahashi et al. significantly advances our understanding of Ventilator-Associated Events (VAEs) by using advanced causal modeling. Their findings firmly establish that VAEs are clinically significant events... read more

Postoperative Steroids Linked to Longer Time on Ventilator

Postoperative use of systemic corticosteroids was linked to a longer duration of mechanical ventilation (MV), but it did not increase mortality or overall complications. While the study's initial analysis did not show... read more

Increased Driving Pressure During Assisted Ventilation for Hypoxemic Respiratory Failure Is Associated with Lower ICU Survival

Driving pressure is marker of severity and a possible target for lung protection during controlled ventilation, but its value during assisted ventilation is unknown. Inspiratory holds provide an estimate of driving pressure... read more

Mechanical Power Impact Normalized to Predicted Body Weight on Outcomes in Pediatric ARDS

Higher mechanical power (MP) was associated with fewer ventilator (VFD) and ICU free days (IFD). The causal effect of MP on VFD and IFD was fully mediated by the impairment in oxygenation. This is a post-hoc analysis of... read more

Ventilation Practices in ABI Patients and Association with Outcomes

Current mechanical ventilation practices for patients with acute brain injury (ABI) are poorly defined. This study aimed to describe ventilator settings/parameters used in intensive care units (ICUs) and evaluate their association... read more

Oral Health Care and VAP in ICU Patients

Both Zataria Multiflora (ZM) and Chlorhexidine (CHG) and CHG alone reduce ventilator-associated pneumonia (VAP) incidence and improve the oral health status of mechanically ventilated patients. However, the combination of... read more

Electrical Impedance Tomography for PEEP Titration in ARDS Patients

ARDS patients may benefit from electrical impedance tomography (EIT)-guided positive end-expiratory pressure (PEEP) titration. The real-time bedside assessment of regional ventilation provided by EIT may result in improved... read more

Intubate Patients with Sepsis Before Midnight or When the Time Comes?

The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more

Ventilator-associated Lung Disease: A Complex Reality in the ICU

Mechanical ventilation, by tracheal intubation or tracheostomy, is the common supplementary treatment for several reasons for hospitalization. Since the advent of long-term mechanical ventilation during the polio epidemic. In... read more

Ventilator-associated Lung Disease: A Complex Reality in the ICU

Implementing a Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy Team Reduces Length of Stay and Hospital Costs

Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more

Predictors of Weaning Failure in Ventilated ICU Patients

Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more