Predictors of Weaning Failure in Ventilated ICU Patients

Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more

Predictive Value of Diaphragm and Lung Ultrasonography for Weaning Failure in Critically Ill Patients with ARF Due to COVID-19 Pneumonia

Patients undergoing mechanical ventilation due to respiratory failure require a comprehensive approach to determine the optimal timing for weaning from ventilatory support. Evaluating respiratory mechanics, maximal muscle... read more

Assessment of Respiratory Muscles, Lung Parenchyma, and Cardiac Function by Ultrasound for Predicting Weaning Failure in Critically Ill Adults

Parasternal intercostal muscle thickening fraction (PMTF) has good discriminatory power to predict weaning outcomes (area under the receiver operating characteristic curve: 0.74 [0.59–0.88]). Pre-SBT PMTF had similar power... read more

Respiratory Effort in Mechanical Ventilation Weaning Prediction

This study demonstrates that PMI and ΔPocc are effective in predicting weaning outcomes in patients with DT≥2mm. The effectiveness of P0.1 in assessing weaning is also significantly higher in this subgroup. These findings... read more

Low-Frequency Ventilation May Facilitate Weaning in ARDS Treated with ECMO

Low-frequency ventilation is comparable to conventional protective ventilation in patients with ARDS who have been treated with ECMO. However, low-frequency ventilation may support weaning from invasive mechanical ventilation... read more

Critical Care Device Series: External Ventricular Drain

External ventricular drainage (EVD), is one of the most frequently performed neurosurgical procedures, with approximately 20,000 performed annually. EVD placement is often considered a lifesaving measure to alleviate severe... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

Mechanical Ventilation in the ICU: A New Approach and Treatment

In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more

Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care

Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care

This book establishes the indications for the use of NIV in the context of weaning from invasive mechanical ventilation. It provides a comprehensive overview of key topics relevant for correct practical application, including... read more

Weaning from Ventilation and Extubation of Children in Critical Care

Weaning from Ventilation and Extubation of Children in Critical Care

By reading this article, you should be able to: - Identify the predictors of successful extubation in pediatric ICU (PICU) patients. - Describe the factors affecting mechanical ventilator weaning in PICU patients. -... read more

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Now in full-colour, this eagerly-anticipated second edition continues to be the most comprehensive resource available on non-invasive ventilation (NIV), both in the hospital and at home. Reflecting a global perspective with... read more

Weaning Methods From Mechanical Ventilation in Adult Patients

Weaning Methods From Mechanical Ventilation in Adult Patients

In general consideration, our study provided evidence that weaning with proportional assist ventilation has a high probability of being the most effective ventilation mode for patients with mechanical ventilation regarding... read more

Adrenal Insufficiency in Patients Taking Benralizumab as Corticosteroid Sparing Therapy

Adrenal Insufficiency in Patients Taking Benralizumab as Corticosteroid Sparing Therapy

A personalised regimen of tapering oral corticosteroids in the presence of the anti-IL5 receptor α-directed cytolytic monoclonal antibody benralizumab can help to achieve elimination or dose reduction of oral corticosteroids... read more

Validation of RSBI Displayed by the Ventilator vs. Standard Technique in Patients with Readiness for Weaning

Validation of RSBI Displayed by the Ventilator vs. Standard Technique in Patients with Readiness for Weaning

The ventilator significantly overestimates the RSBI value compared to the standard technique by Wright spirometer. The average RSBI vent value among 5 time points (0, 15, 30, 45, and 60 s) was found to best correlate with... read more

NIV After Early Extubation Reduces Total Days Spent on i-MV

NIV After Early Extubation Reduces Total Days Spent on i-MV

Patients recovering from an episode of hypoxemic acute respiratory failure (hARF) may benefit from a weaning strategy based on early extubation followed by immediate noninvasive ventilation (NIV) application. Compared... read more

Replacement of Fentanyl Infusion by Enteral Methadone Decreases the Weaning Time From Mechanical Ventilation

Replacement of Fentanyl Infusion by Enteral Methadone Decreases the Weaning Time From Mechanical Ventilation

The introduction of enteral methadone during weaning from sedation and analgesia in mechanically ventilated patients resulted in a decrease in the weaning time from mechanical ventilation (MV). A double-blind randomized... read more

Ventilator Weaning and Discontinuation Practices for Critically Ill Patients

Ventilator Weaning and Discontinuation Practices for Critically Ill Patients

In this observational study of invasive mechanical ventilation discontinuation in 142 ICUs in Canada, India, the UK, Europe, Australia/New Zealand, and the US from 2013 to 2016, weaning practices varied internationally. Among... read more