In patients requiring intubation from acute salicylate toxicity, hemodialysis should be considered as part of management, as this is associated with decreased mortality.

Salicylates are common substances that can be purchased over the counter. They are readily available, and in the setting of an overdose, can be fatal. Initially, as salicylates are metabolized, they can induce a respiratory alklalosis. This is then followed by an anion gap metabolic acidosis.

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