This large observational study did not support an association between intravenous contrast media and adverse in-hospital outcomes in patients with septic dialysis-requiring acute kidney injury (AKI-D). Further studies are warranted to assess the generalizability.

From 3,782 and 6,619 patients with septic AKI-D with and without intravenous contrast exposure, respectively, 3,485 propensity score-matched pairs were generated.

This was a retrospective observational study using the Japanese Diagnosis Procedure Combination inpatient database between January 2011 and December 2016.

We identified patients with septic AKI who began continuous renal replacement therapy (RRT) within 2-days of admission and underwent computed tomography.

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