Intraosseous vs. Intravenous Vascular Access During CPR for Out-of-hospital Cardiac Arrest

sjtrem.biomedcentral.com March 13, 2021

intraosseous-versus-intravenous-vascular-access-during-cardiopulmonary-resuscitation-for-out-of-hospital-cardiac-arrest

The meta-analysis revealed no significant association between types of vascular access and neurological outcomes at hospital discharge among out-of-hospital Cardiac Arrest (OHCA) patients. Time to intervention was identified to be an important outcome moderator in this meta-analysis of observation studies.

These results call for the need for future clinical trials to investigate the unbiased effect of IO use on OHCA CPR.

Nine retrospective observational studies involving 111,746 adult OHCA patients were included.

Most studies were rated as high quality according to Newcastle-Ottawa Scale. The pooled results demonstrated no significant association between types of vascular access and the primary outcome.

In subgroup analysis, time to intervention was noted to be positively associated with the pooled OR of achieving the primary outcome.