The long-term survival of mechanically ventilated patients with severe COVID-19 reaches more than 50% and may help to provide individualized risk stratification and potential treatments.

868 patients were included (median age, 64 years 72% male).

Severity at ICU admission, estimated by SAPS3, was 56 points [IQR 50–63].

Prior to intubation, 26% received some type of noninvasive respiratory support.

The unadjusted overall 180-day survival rates was 59% (95% CI 56–62%).

Retrospective, multicentre, national cohort study between March 8 and April 30, 2020 in 16 intensive care units (ICU) in Spain.

Participants were consecutive adults who received invasive mechanical ventilation for COVID-19.

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