No IV Hydration for Contrast Nephropathy? AMACING Trial Challenges a Cornerstone of Prophylaxis

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A Dutch study undercutting the established role of hydration in preventing kidney damage during procedures is raising eyebrows. Dutch researchers are calling into question one of the cornerstone practices of cath labs and radiation suites around the globe: prophylactic hydration to prevent contrast-induced nephropathy. In a randomized trial comparing intravenous saline to no hydration, patients at high risk for contrast nephropathy gained no added protection from hydration during elective procedures that required iodinated contrast.

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