Optimal Duration of Mechanical Ventilation and Influencing Factors Following Mandibular Distraction Osteogenesis in Infants

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Mandibular distraction osteogenesis (MDO) is an effective treatment for tongue-based airway obstruction in infants with severe Pierre Robin sequence (PRS).

Most infants receiving MDO require postoperative mechanical ventilation (MV) to assist breathing.

Optimal MV time for each individual patient and factors influencing the time must be identified to guide clinical decision-making.

A retrospective analysis was performed on 75 infants with PRS receiving MDO from November 2016 to August 2018.

26 were females and 47 were males.

Data extracted from the hospital information system included sex, age, weight, history of preterm labor, preoperative pulmonary infection, laryngomalacia/tracheomalacia, laryngoscope exposure classification, anesthesia duration, operation duration, postoperative treatment site, situation of distraction, postoperative complications and MV duration.

Statistical analyses were conducted to investigate the potential associations of these factors with MV time.

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