Outcomes of Catheter-Related Arterial and Venous Thrombosis After Enoxaparin Therapy in Neonates and Infants With Congenital Heart Disease

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A high proportion of vascular catheter-related thrombi identified in infants with congenital heart disease resolve with enoxaparin treatment. In all patients with thrombosis, arterial versus venous thrombosis is associated with greater odds of resolution.

One-hundred fifty-six events of central catheter-related arterial and venous thrombosis were included in the study.

Arterial thrombi accounted for 109 (69.9%) and venous thrombi for 47 (30.1%) of the events. Femoral vessels were the most commonly affected site (88.5%).

Therapeutic outcomes were analyzed in 106 events, excluding those without follow-up imaging.

The analysis was stratified by age into neonates and infants and catheter types into arterial and venous catheter groups.

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