It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized nutrition care delivering the right nutrition dose, in the right patient, at the right time to optimize clinical outcome.

Adequately resuscitated patients on vasopressors can and likely should receive trophic early EN and this was recently associated with reduced mortality. Patients paralyzed with neuromuscular blocking agents can and should receive early EN as this was recently associated with reduced mortality/hospital length of stay.

Proned patients can safely receive EN.

All ICU nutrition delivery, including EN, should be objectively guided by indirect calorimetry (IC) measures.

This is now possible with the new availability of a next-generation IC device.

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