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Parenteral Anticoagulation Not Associated with Reduced Risk of Ischemic Stroke Among Patients with Atrial Fibrillation During Sepsis

Parenteral Anticoagulation Not Associated with Reduced Risk of Ischemic Stroke Among Patients with Atrial Fibrillation During Sepsis

Among patients with Atrial Fibrillation (AF) during sepsis, parenteral anticoagulation was not associated with reduced risk of ischemic stroke and was associated with higher bleeding rates.

Of 113,511 patients hospitalized with AF and sepsis, 38,582 were included in our primary analysis.

A total of 13,611 patients received parenteral anticoagulants, while 24,971 did not.

Hospital utilization rates of parenteral anticoagulants for AF during sepsis varied.

CHA2DS2VASc scores poorly discriminated the risk of ischemic stroke during sepsis.

Parenteral anticoagulants administered in doses greater than those used for prophylaxis of venous thromboembolism.

CriticalCare.news
September 6, 2019

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