Several studies have demonstrated coagulation changes in patients with COVID-19, especially in those with severe disease, and this is associated with a worse prognosis.

Emerging data, alongside recent clinical experience, have suggested a high prevalence of venous thromboembolism (VTE) in patients with COVID-19.

Disseminated intravascular coagulation (DIC) is a late disease event in COVID-19 infection, is associated with multiple organ failure and should be treated as per standard guidance.

This document provides guidance on the prevention, diagnosis and management of VTE in patients with COVID-19 who are seen in hospital.

The effectiveness of most interventions in the context of COVID-19 is currently uncertain. This guide is informed by emerging information about COVID-19 management as well as best available evidence from non-COVID-19 patients. It will be updated when further evidence is available.

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