Serum Creatinine in the Critically Ill Patient With Sepsis

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sepsis

A 73-year-old man underwent esophageal resection for cancer. He had a history of hypertension that was treated with an angiotensin receptor blocker.

Preoperative estimated glomerular filtration rate (GFR) was 98 mL/min/1.73 m2.

On the second postoperative day, body temperature was 38.6°C.

Chest x-ray revealed bilateral lung consolidations consistent with pneumonia.

Blood pressure decreased from 145/72 mm Hg to 96/53 mm Hg with a heart rate of 105/min.

The patient was admitted to the intensive care unit (ICU) with acute respiratory failure and was placed on mechanical ventilation.

In the ICU, urine output was 50 mL over 3 hours. On day 3, he received 4.5 L of Ringer lactate over 12 hours.

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