In the second of a series of manuscripts subsequent to the original article, members with expertise in the subjects expound upon the three identified priorities related to fluid resuscitation and vasopressor therapies. This analysis summarizes what is known and what were identified as ongoing and future research.

In an attempt to define priorities for research within the field of sepsis, SSC created a research committee that was charged with developing a list of research questions related to sepsis. This led to the joint publication of “Surviving Sepsis Campaign Research Priorities for Sepsis and Septic Shock” in Critical Care Medicine and Intensive Care Medicine in August 2018.

The initial document presented a broad overview, identifying 26 questions to explore as research priorities in several domains with an explicit intention to publish separate papers with more detailed descriptions for each domain in the future.

This article is the second in a series of manuscripts (following a prior effort devoted to basic science research), which will expand upon the three research questions related to fluid resuscitation and vasopressors originating from the broader publication.

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