This study highlights the significant prognostic utility of nutritional status evaluation in septic patients admitted to internal medicine wards.

Among the tools evaluated, the mNUTRIC score—likely because of its dual focus on malnutrition and illness severity—emerged as the most robust predictor of in-hospital mortality, demonstrating its capacity to effectively stratify risk and guide clinical decision-making.

The identification of a specific cutoff value of 4.5 points for the mNUTRIC score enhances its clinical applicability, providing a clear threshold for assessing nutritional risk in septic patients.

Its simplicity and reliance on readily available clinical parameters make it accessible in resource-limited settings and suitable for early identification of high-risk patients, potentially guiding timely nutritional and therapeutic interventions.

Importantly, our study supports the expansion of its utility beyond the ICU, highlighting its applicability in internal medicine settings.

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