Vitamin C for Sepsis

healthmanagement.org

Dr. Alpha A. Fowler of Virginia Commonwealth University presented findings from the CITRIS-ALI trial that studied the role of vitamin C in patients with septic ARDS. The findings were presented @ESICM in Berlin and have just been published in JAMA.

The CITRIS-ALI randomised trial addressed the use of high dose intravenous vitamin C to study the effects of organ failure and the effects of vitamin C on inflammation and vascular injury biomarkers in patients with sepsis inducted ARDS.

As Dr. Fowler pointed out, there is a global scourge of sepsis. Fleischmann and colleagues in 2016 reported that in first and second world countries, the incidence of ARDS was 31 million individuals with greater than 6 million deaths.This study did not include third world countries where medical care is less than what is practiced in first and second world countries.

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