Which Injured Patients with Moderate Fibrinogen Deficit Need Fibrinogen Supplementation?

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We have shown in this study an association between shock parameters and fibrinogen administration. Further studies are needed to determine how these parameters may be used to guide fibrinogen administration in trauma patients with moderate fibrinogen deficit (MFD).

1,076 patients were included in the study and 266 (27%) had MFD-C, among them, 122/266 (46%) received fibrinogen.

Patients with MFD-C who received fibrinogen were more severely injured and had more impaired vital signs.

Linear regression analysis found a positive correlation between fibrinogen level and FIBTEM-A5 (r: 0.805).

Prospective analysis of retrospectively collected data from a trauma registry (01/2011–12/2019).

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